Estimated change (95% CI) from baseline in the percentage points of neurological symptoms reported at each of nine successive collected time points, shown separately for non-applicators and applicators
| Time intervals | Non-applicators adjusted models* | Applicators adjusted models* | Change in difference between applicators and non-applicators relative to difference in baseline | ||||
|---|---|---|---|---|---|---|---|
| 1 | Days from baseline (day 0–14) 2 June–14 June 2010 | B (percentage of symptoms) (95% CI) | p Value | B (percentage of symptoms) (95% CI) | p Value | B (percentage of symptoms) (95% CI) | p Value |
| 2 | 17–21 (19–23 June) | −2.74 (−4.61 to −0.86) | 0.004 | 4.08 (0.18 to 7.97) | 0.040 | 6.81 (2.47 to 11.15) | 0.002 |
| 3 | 24–28 (26–30 June) | −2.68 (−5.18 to 0.17) | 0.004 | 12.57 (7.75 to 17.38) | <0.001 | 15.25 (9.80 to 20.69) | <0.001 |
| 4 | 31–35 (3–7 July) | 4.45 (−0.80 to 9.71) | 0.10 | 14.06 (9.21 to 18.90) | <0.001 | 9.60 (2.44 to 16.77) | 0.009 |
| 5 | 38–42 (10–14 July) | −2.28 (−4.75 to 0.17) | 0.07 | 22.83 (19.25 to 26.40) | <0.001 | 25.11 (20.79 to 29.43) | <0.001 |
| 6 | 45–48 (17–21 July) | 0.46 (−2.37 to 3.30) | 0.75 | 28.80 (24.27 to 33.35) | <0.001 | 28.35 (22.98 to 33.72) | <0.001 |
| 7 | 52–59 (24–31 July) | 4.95 (1.63 to 8.28) | 0.003 | 24.01 (19.92 to 28.09) | <0.001 | 19.05 (13.80 to 24.30) | <0.001 |
| 8 | 63–77 (4–18 August) | 14.49 (11.45 to 17.55) | <0.001 | 30.10 (26.53 to 33.66) | <0.001 | 15.60 (10.95 to 20.26) | <0.001 |
| 9 | 80–94 (21 August–4 September) | 12.08 (8.72 to 15.44) | <0.001 | 29.17 (25.22 to 33.13) | <0.001 | 17.09 (11.93 to 22.25) | <0.001 |
| 10 | 105–217 (22 September–5 January) | 9.22 (6.12 to 12.32) | <0.001 | 18.45 (14.30 to 22.59) | <0.001 | 9.22 (4.12 to 14.33) | <0.001 |
*Models adjusted for number of days worked for applying pesticides, years of pesticide use at home, age, education and income level. Chlorpyrifos application time intervals are in bold.