MPM vs other cancers | MPM vs benign diseases | |
---|---|---|
Studies (reference numbers) | 23, 34, 36, 41, 42, 48 | 36, 41, 42, 48 |
Sensitivity (95% CI) | 0.75 (0.69 to 0.80) | 0.75 (0.67 to 0.82) |
Heterogeneity* (p value) | 1.36 (0.929) | 1.08 (0.783) |
Specificity (95% CI) | 0.76 (0.71 to 0.82) | 0.87 (0.80 to 0.93) |
Heterogeneity (p value) | 4.88 (0.430) | 6.74 (0.081) |
PLR (95% CI) | 2.95 (2.32 to 3.75) | 4.74 (2.30 to 9.76) |
Heterogeneity (p value) | 4.83 (0.437) | 7.01 (0.071) |
NLR (95% CI) | 0.34 (0.27 to 0.43) | 0.30 (0.22 to 0.40) |
Heterogeneity (p value) | 1.94 (0.857) | 1.83 (0.608) |
DOR (95% CI) | 8.96 (5.78 to 13.89) | 16.87 (6.79 to 41.92) |
Heterogeneity (p value) | 3.34 (0.648) | 5.26 (0.154) |
AUC (SEM) | 0.809 (0.025) | 0.818 (0.050) |
*Q value.
AUC, area under curve; DOR, diagnostic OR; MPM, malignant pleural mesothelioma; NLR, negative likelihood ratio; PLR, positive likelihood ratio.