Patient characteristics
| Variable | All patients (n=2746) | No warfarin (n=1475) | Warfarin (n=1271) |
|---|---|---|---|
| Age, mean (SD)† | 74.3 (12.3) | 71.1 (13.4) | 78.0 (9.8)** |
| Gender, male (%)† | 52.8 | 58.0 | 46.9** |
| CHA2DS2-VASc, mean (SD)† | 3.1 (1.9) | 2.5 (1.8) | 3.8 (1.8)** |
| CHADS2, mean (SD) † | 1.6 (1.4) | 1.2 (1.3) | 2.1 (1.4)** |
| Myocardial infarction (%) | 15.7 | 12.1 | 19.8** |
| Angina pectoris (%) | 21.7 | 18.4 | 25.5** |
| Coronary heart disease (%) | 21.7 | 17.6 | 26.5** |
| Congestive heart failure (%) | 28.6 | 19.0 | 39.7** |
| Hypertension (%) | 14.3 | 10.3 | 19.0** |
| Ischaemic stroke (%) | 13.7 | 9.2 | 18.9** |
| Transient ischaemic attack (%) | 11.8 | 9.6 | 14.2** |
| Thromboembolism (%) | 0.7 | 0.1 | 1.4** |
| Peripheral vascular disease (%) | 7.2 | 4.5 | 10.5** |
| Atherosclerosis of aorta (%) | 0.1 | 0.2 | 0.1 |
| Neoplasm (%) | 1.1 | 0.9 | 1.4 |
| Liver disease (%) | 0.1 | 0.1 | 0.2 |
| Kidney disease (%) | 0.3 | 0.5 | 0.2 |
| Diabetes (%) | 21.6 | 17.1 | 26.9** |
| Intracerebral haemorrhage (%) | 0.1 | 0.1 | 0 |
| Intracranial bleed (%) | 0.1 | 0.1 | 0.1 |
| Gastrointestinal bleed (%) | 0.3 | 0.2 | 0.3 |
| Use of home nursing services (%) | 24.7 | 17.4 | 33.1** |
| Had died by June 2012 (%) | 9.3 | 8.0 | 10.9* |
| Follow-up time‡ | 353.5 (51.8) | 357.5 (42.6) | 348.9 (60.5)** |
*p<0.05, **p<0.001 mark statistically significant differences between warfarin users and non-users.
†Data missing for eight patients in ‘no warfarin’ group.
‡365 days unless the patient died within the study period.