Estimated marginal effects of policy changes, patient characteristics and inpatient facility characteristics on oral anticoagulation therapy initiation
| Adjusted for patient characteristics | Adjusted for patient and facility characteristics | |||
|---|---|---|---|---|
| Adjusted results | ||||
| Postperiod | −0.04* | (−0.07 to −0.01) | −0.03* | (−0.06 to −0.00) |
| Treatment group | −0.39*** | (−0.43 to −0.35) | −0.38*** | (−0.42 to −0.34) |
| Negative control | −0.45*** | (−0.54 to −0.36) | −0.45*** | (−0.54 to −0.36) |
| Post-treatment | 0.10** | (0.04 to 0.17) | 0.11** | (0.04 to 0.18) |
| Post-negative control | −0.03 | (−0.19 to 0.13) | −0.03 | (−0.19 to 0.13) |
| Patient characteristics | ||||
| 18–40 years | 0.03 | (−0.03 to 0.09) | 0.03 | (−0.02 to 0.09) |
| 61–70 years | −0.01 | (−0.04 to 0.02) | −0.01 | (−0.04 to 0.02) |
| 71+ years | −0.10*** | (−0.13 to −0.07) | −0.10*** | (−0.14, −0.07) |
| Gender (male) | 0.02* | (0.00 to 0.04) | 0.03** | (0.01 to 0.05) |
| Charlson (0) | 0.01 | (−0.03 to 0.06) | 0.01 | (−0.03 to 0.05) |
| Charlson (2) | −0.04* | (−0.07 to −0.00) | −0.04* | (−0.07 to −0.00) |
| Charlson (3–4) | −0.02 | (−0.06 to 0.03) | −0.01 | (−0.06 to 0.03) |
| Charlson (5+) | −0.13*** | (−0.17 to −0.09) | −0.12*** | (−0.17 to −0.08) |
| CHADS2 (0–1) | −0.02 | (−0.05 to 0.02) | −0.01 | (−0.05 to 0.03) |
| CHADS2( 3–4) | −0.05* | (−0.09 to −0.01) | −0.04* | (−0.08 to −0.00) |
| CHADS2 (5+) | −0.04 | (−0.11 to 0.04) | −0.03 | (−0.10 to 0.04) |
| Rural | 0.02 | (−0.03 to 0.06) | 0.01 | (−0.05 to 0.07) |
| Micropolitan | 0.01 | (−0.03 to 0.04) | −0.00 | (−0.05 to 0.04) |
| 0 pre-event visits | −0.05* | (−0.09 to −0.00) | −0.04 | (−0.09 to 0.00) |
| 2+ pre-event visits | 0.06*** | (0.03 to 0.09) | 0.05*** | (0.02 to 0.08) |
| Facility characteristics | ||||
| Primary stroke centre | −0.01 | (−0.06 to 0.04) | ||
| GWTG participation | −0.01 | (−0.03 to 0.02) | ||
| 4–99 beds | −0.04 | (−0.09 to 0.00) | ||
| 500+ beds | −0.04 | (−0.08 to 0.00) | ||
| 25+ miles | −0.10*** | (−0.16 to −0.05) | ||
| Rural provider | 0.07 | (−0.01 to 0.16) | ||
| Micropolitan provider | 0.04 | (−0.01 to 0.09) | ||
| Observations | 5235 | 5235 | ||
95% CIs in parenthesis.
*p<0.05.
**p<0.01.
***p<0.001.
CHADS2, C—congestive heart failure, H—hypertension, A—>75 years, D—diabetes mellitus, S—prior stroke or stroke symptoms, GWTG, Get With The Guidelines