Table 1

Case definitions for CFS/ME

Case definitions (chronologically)Developed from other criteria or definitions?Institution and country of first authorCITATIONS*
ISI/Google Scholar
CDC-1988/Holmes et al20Centers for Disease Control, Atlanta, USA1106/1542
ME-1988/Ramsey42Royal Free Hospital, London, UK6/51
London-1990/Dowsett et al37Royal Free Hospital, London, UK55/88
Australian-199044The Prince Henry Hospital, Little Bay, Australia230/343
Postviral fatigue syndrome-199043Raigmore Hospital, Inverness, UK14/28
Oxford-199140University of Oxford, Oxford, UK476/667
London ME-1994/National Task Force Guidelines48National Task Force, Bristol, UKNo records
CDC-1994/Fukuda et al39CDC-1988Centers for Disease Control, Atlanta, USA1860/3006
Working case definition-199638CDC-1988Brigham and Women's Hospital Massachusetts, USA78/138
CFS-199849CDC-1994Medical College of Wisconsin, USA8/23
Canadian-200322Royal College of Physicians and Surgeons of Canada, Canada69/233
Empirical CDC-2005/Reeves et al63CDC-1994Centers for Disease Control and Prevention, Atlanta, USA73/154
Empirical-200741DePaul University, Chicago, USA5/14
Brighton Collaboration-200735Centers for Disease Control and Prevention, Atlanta, USA1/5
NICE-2007 Guidelines46National Institute for Health and Clinical Excellence, London, UKNo records/23†
The Nightingale Definition of ME-2007/Hyde45The Nightingale Research Foundation, CanadaNo records/5
ECD-200834Southampton, Hampshire, UK2/4
Revised Canadian-201047CDC-1994, Empirical CDC-2005, Canadian-2003DePaul University, Illinois, USA8/18
ICC-201123Canadian-2003Independent, Canada4/16
ME-201133London-1990, ME-1988, The Nightingale Definition of ME-2008DePaul University, Illinois, USA1/1
  • *Searched 23 May 2012.

  • †Summary of the NICE Guidelines in: diagnosis and management of chronic fatigue syndrome or myalgic encephalomyelitis (or encephalopathy): summary of NICE guidance. BMJ 2007;335:446.

  • CFS, chronic fatigue syndrome; ICC, International Consensus Criteria; ME, myalgic encephalomyelitis; ECD, epidemiological CFS/ME definition.