Baseline characteristics*
| Demographics | Angiography (n=222) | SPECT (n=224) | Cardiac MRI (n=226) | Stress ECHO (n=226) |
|---|---|---|---|---|
| Mean (SD) age (years) | 60.7 (9.1) | 62.1 (9.5) | 62.2 (9.0) | 61.9 (9.9) |
| Males (%) | 149 (67%) | 157 (70%) | 153 (68%) | 160 (71%) |
| History/risk factors | ||||
| Previous MI (%) | 63 (28%) | 52 (23%) | 69 (31%) | 59 (26%) |
| Previous CVA (%) | 10 (5%) | 13 (6%) | 8 (4%) | 12 (5%) |
| Diabetes (%) | ||||
| IDDM | 12 (5%) | 8 (4%) | 11 (5%) | 5 (2%) |
| NIDDM | 16 (7%) | 18 (8%) | 21 (9%) | 22 (10%) |
| Family history CAD | 60 (27%) | 55 (25%) | 63 (28%) | 59 (26%) |
| Smoking history (%) | ||||
| <25 pack-years | 149 (67%) | 162 (72%) | 148 (65%) | 155 (69%) |
| ≥25 pack-years | 73 (33%) | 62 (28%) | 78 (35%) | 71 (31%) |
| Treated hyperlipidaemia (%) | 164 (74%) | 171 (76%) | 179 (79%) | 179 (79%) |
| Treated hypertension (%) | 117 (53%) | 132 (59%) | 115 (51%) | 129 (57%) |
| Exercise tolerance using the modified Bruce protocol | ||||
| Mean (SD) total exercise time (min) | 11.29 (4.56) | 10.46 (4.41) | 10.43 (4.43) | 10.89 (4.36) |
| ECG changes on exercise test | ||||
| 1–2 mm ST depression with symptoms | 53 (24%) | 43 (19%) | 54 (24%) | 57 (25%) |
| ≥2 mm ST depression without symptoms | 16 (7%) | 24 (11%) | 20 (9%) | 24 (11%) |
| ST elevation†/no change | 153 (69%) | 157 (70%) | 152 (67%) | 145 (64%) |
| CCS class | ||||
| 0–I | 60 (27%) | 54 (24%) | 78 (35%) | 58 (26%) |
| II | 138 (62%) | 144 (64%) | 122 (54%) | 132 (58%) |
| III–IV | 24 (11%) | 26 (12%) | 26 (11%) | 36 (16%) |
*There were no significant differences between the groups in any variable.
†ST elevation was observed in three angiography, two CMR and one ECHO patients.
CAD, coronary artery disease; CCS, Canadian Cardiovascular Society CVA; cerebrovascular accident; IDDM, Insulin-dependent diabetes mellitus; MI, myocardial infarction; NIDDM, non-insulin-dependent diabetes mellitus; SPECT, single photon emission CT.