Associations between previous diagnosis received in secondary mental healthcare and stage at cancer diagnosis (N=28 477)
| Variables | Cancer stage at diagnosis N (%) | Unadjusted OR for advanced cancer stage (95% CI) | Age- and gender-adjusted OR for advanced cancer stage (95% CI) | Fully adjusted OR for advanced cancer stage* (95% CI) | |
|---|---|---|---|---|---|
| Localised stage (N=18 290) | Advanced stage (N=10 187) | ||||
| SMI† | |||||
| No | 18 208 (64.22) | 10 144 (35.78) | Ref | Ref | Ref |
| Yes | 82 (65.60) | 43 (34.40) | 0.94 (0.65 to 1.36) | 1.01 (0.70 to 1.47) | 0.94 (0.64 to 1.39) |
| Schizophrenia | |||||
| No | 18 233 (64.24) | 10 151 (35.76) | Ref | Ref | Ref |
| Yes | 57 (61.29) | 36 (38.71) | 1.13 (0.75 to 1.72) | 1.23 (0.81 to 1.88) | 1.10 (0.71 to 1.71) |
| Bipolar disorder | |||||
| No | 18 266 (64.21) | 10 180 (35.79) | Ref | Ref | Ref |
| Yes | 24 (77.42) | 7 (22.58) | 0.52 (0.22 to 1.22) | 0.55 (0.24 to 1.30) | 0.60 (0.25 to 1.42) |
| Schizoaffective disorder | |||||
| No | 18 286 (64.22) | 10 186 (357.8) | Ref | Ref | Ref |
| Yes | 4 (80.0) | 1 (20.0) | 0.45 (0.05 to 4.02) | 0.47 (0.05 to 4.38) | 0.47 (0.04 to 4.95) |
| Depression | |||||
| No | 18 184 (64.22) | 10 129 (35.78) | Ref | Ref | Ref |
| Yes | 106 (64.63) | 58 (36.37) | 0.98 (0.71 to 1.35) | 0.91 (0.66 to 1.26) | 0.90 (0.64 to 1.27) |
| Dementia | |||||
| No | 18 229 (64.26) | 10 137 (35.74) | Ref | Ref | Ref |
| Yes | 61 (54.95) | 50 (45.05) | 1.47 (1.01 to 2.14)‡ | 1.00 (0.68 to 1.46) | 1.23 (0.82 to 1.85) |
| Substance use disorders | |||||
| No | 18 260 (64.23) | 10 171 (35.77) | Ref | Ref | Ref |
| Yes | 30 (65.22) | 16 (34.78) | 0.96 (0.52 to 1.76) | 1.01 (0.55 to 1.87) | 0.99 (0.52 to 1.89) |
| Anxiety disorders | |||||
| No | 18 263 (64.22) | 10 173 (35.78) | Ref | Ref | Ref |
| Yes | 27 (65.85) | 14 (34.14) | 0.93 (0.49 to 1.78) | 0.98 (0.51 to 1.89) | 1.15 (0.58 to 2.28) |
| Personality disorders | |||||
| No | 18 282 (64.24) | 10 179 (35.76) | Ref | Ref | Ref |
| Yes | 8 (50.00) | 8 (50.00) | 1.80 (0.67 to 4.79) | 2.15 (0.80 to 5.76) | 1.78 (0.65 to 4.88) |
*Adjust for age, gender, type of cancer, year of cancer diagnosis, primary care trust, ethnicity and deprivation score for income.
†SMI: schizophrenia, bipolar disorder or schizoaffective disorder.
‡Statistical significance.
SMI, severe mental illness.