Association of MDD symptoms with suicidal ideation (N=1266)
| MDD symptoms | n (%) | Suicidal ideation (n=34) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Model 1* (non-adjusted) | Model 2† (adjusted) | Model 3‡ (adjusted) | Sensitivity (%) | Specificity (%) | AUC (95% CI) | |||||
| OR (95% CI) | p Value | OR (95% CI) | p Value | OR (95% CI) | p Value | |||||
| Depressive mood | 92 (7.3) | 11.8 (5.8 to 24.2) | <0.01 | 11.5 (5.6 to 23.6) | <0.01 | 11.2 (5.4 to 23.0) | <0.01 | 44.1 | 93.8 | 0.69 (0.66 to 0.71) |
| Loss of interest | 117 (9.2) | 3.2 (1.4 to 7.2) | <0.01 | 3.5 (1.5 to 7.9) | <0.01 | 3.5 (1.5 to 8.0) | <0.01 | 23.5 | 91.2 | 0.57 (0.55 to 0.60) |
| Weight loss | 48 (3.8) | 4.8 (1.8 to 12.9) | <0.01 | 4.9 (1.8 to 13.5) | <0.01 | 5.0 (1.8 to 13.8) | <0.01 | 14.7 | 96.5 | 0.56 (0.53 to 0.58) |
| Insomnia | 455 (35.9) | 2.0 (1.0 to 4.1) | 0.04 | 1.9 (0.9 to 3.8) | 0.07 | 1.8 (0.9 to 3.7) | 0.09 | 52.9 | 64.5 | 0.59 (0.56 to 0.61) |
| Psychomotor agitation | 741 (58.5) | 2.4 (1.1 to 5.2) | 0.04 | 2.2 (0.9 to 5.0) | 0.06 | 2.2 (0.9 to 4.9) | 0.06 | 76.5 | 42.0 | 0.59 (0.56 to 0.62) |
| Fatigue | 920 (72.7) | 2.9 (0.9 to 8.2) | 0.06 | 2.6 (0.9 to 7.6) | 0.07 | 2.6 (0.9 to 7.5) | 0.08 | 61.8 | 84.7 | 0.58 (0.55 to 0.61) |
| Worthlessness | 210 (16.6) | 8.9 (4.4 to 18.1) | <0.01 | 8.6 (4.2 to 17.5) | <0.01 | 8.5 (4.1 to 17.4) | <0.01 | 61.8 | 84.7 | 0.73 (0.71 to 0.76) |
| Concentration loss | 274 (21.6) | 6.3 (3.1 to 12.7) | <0.01 | 6.3 (3.1 to 12.8) | <0.01 | 6.1 (3.0 to 12.5) | <0.01 | 61.8 | 79.5 | 0.71 (0.62 to 0.79) |
Bold typeface indicates statistically significant at p<0.05.
*Model 1 was the crude analysis.
†Model 2 was adjusted for sex and age (used as categorical variables).
‡Model 3 was adjusted for sex, age (used as categorical variables) and lifestyle factors (smoking status, alcohol consumption and exercise).
MDD, major depressive disorder.