Echocardiographic parameters comparing baseline readings with within a month and within a year after the start of anthracycline chemotherapy
| Echocardiographic parameters | Baseline readings | Within a month | Within a year | p Value |
|---|---|---|---|---|
| EF (%) | 69.9±4.3 | 67.3±5.3 | 62.6±9.6 | <0.001 |
| FS (%) | 36.6±2.6 | 35.3±2.8 | 32.9±5.0 | <0.001 |
| PWT (mm) | 6.7±1.3 | 5.8±1.1 | 5.4±1.1 | <0.001 |
| IVS (mm) | 5.9±0.2 | 5.4±1.1 | 4.9±1.0 | <0.001 |
| LVEDD (mm) | 34.5±5.6 | 35.8±5.4 | 37.3±5.8 | <0.001 |
| LVESD (mm) | 22.0±4.2 | 23.4±4.4 | 25.3±5.4 | <0.001 |
| E (cm/s) | 93.7±9.2 | 86.8±10.3 | 85.1±11.5 | <0.001 |
| A (cm/s) | 58.9±6.5 | 63.5±7.5 | 64.6±9.1 | <0.001 |
| E/A ratio | 1.6±1.8 | 1.38±0.21 | 1.3±.33 | <0.001 |
| E′ (cm/s) | 14.1±2.4 | 12.2±2.3 | 11.1±2.5 | <0.001 |
| E/E′ ratio | 6.7±1.05 | 7.17±1.1 | 8.1±2.6 | <0.001 |
| Tei index (MPI) | 0.3±.05 | 0.4±.05 | 0.4±.07 | <0.001 |
| DT | 164.3±15.3 | 171.6±19.8 | 174.7±28.9 | <0.001 |
A, peak flow velocity during atrial contraction; DT, E deceleration time; E, early diastolic mitral peak flow velocity; E′, peak early diastolic myocardial velocity; EF, ejection fraction; FS, fractioning shortening; IVS, interventricular wall thickness; LVEDD, left ventricular (LV) end diastolic diameter; LVESD in mm, LV end systolic diameter; LVESD, LV end systolic diameter; PWT, LV posterior wall thickness; Tei index, MPI=Myocardial performance index.