Table 5

Hospital-driven criteria in the selection of phase II–III trial sites (phase III–IV for medical devices)

MeanUpper 95% CLLower 95% CL
Site personnel experience and training22.023.120.84
Previous experience with site20.021.218.7
Facilities/equipment required by trial19.720.718.7
Hospital approval/contracting system17.418.516.4
Site personnel language proficiency10.811.710.0
Hospital quality assurance process10.110.99.2
  • Respondents (N=341) were asked to rate hospital-driven criteria by dividing 100 points across six criteria potentially used when selecting trial sites for phase III studies: Pharma, Biotech, CROs and CTUs answered for phase III studies. Medical device and all others answered for phase IV studies. There was evidence of a statistically significant difference in the level of importance of the six criteria (p<0.0001).

  • CL, confidence limit; CROs, clinical research organisations; CTUs, clinical trial units.