Table 2

HRs (and 95% CIs) of functional limitations for mortality*

CovariatesOther-cause mortality (number of deaths=436)Breast cancer mortality (number of deaths=317)
BaselineDeclineBaselineDecline
Model 1
 African-American1.23 (0.91 to 1.66)1.19 (0.88 to 1.62)1.04 (0.76 to 1.44)1.08 (0.78 to 1.49)
Model 2
 African-American1.19 (0.87 to 1.62)1.19 (0.88 to 1.62)1.12 (0.81 to 1.55)1.08 (0.78 to 1.49)
 Difficulty pushing/pulling large objects (yes/no)1.34 (1.04 to 1.73)0.98 (0.67 to 1.43)0.77 (0.58 to 1.03)1.41 (0.93 to 2.13)
 Difficulty stooping/crouching/kneeling (yes/no)1.02 (0.77 to 1.35)0.97 (0.65 to 1.45)1.39 (0.99 to 1.94)0.94 (0.56 to 1.57)
 Difficulty lifting less than 10 pounds (yes/no)0.92 (0.68 to 1.25)0.91 (0.53 to 1.56)1.05 (0.72 to 1.53)1.27 (0.65 to 2.48)
 Difficulty lifting ≥10 pounds (yes/no)0.99 (0.75 to 1.30)1.07 (0.71 to 1.60)0.78 (0.56 to 1.07)1.20 (0.76 to 1.89)
 Difficulty extending arm above shoulder level (yes/no)0.97 (0.72 to 1.31)0.94 (0.56 to 1.58)0.85 (0.58 to 1.23)0.92 (0.49 to 1.76)
 Difficulty writing/handling small objects (yes/no)1.56 (1.00 to 2.44)0.47 (0.22 to 1.03)1.61 (0.95 to 2.73)1.19 (0.53 to 2.68)
 Difficulty standing more than 15 min (yes/no)0.81 (0.58 to 1.13)1.33 (0.87 to 2.02)0.91 (0.62 to 1.35)1.58 (0.96 to 2.62)
 Difficulty sitting more than an hour (yes/no)0.77 (0.49 to 1.22)1.75 (0.99 to 3.09)1.04 (0.63 to 1.73)2.06 (1.13 to 3.76)
 Difficulty going up/down a flight of stairs (yes/no)1.29 (0.93 to 1.78)1.18 (0.82 to 1.69)1.07 (0.70 to 1.63)0.61 (0.37 to 1.01)
 Difficulty walking half a mile (yes/ no)1.60 (1.19 to 2.14)1.34 (0.90 to 2.00)1.24 (0.88 to 1.77)1.32 (0.82 to 2.13)
Model 3
 African-American1.22 (0.90 to 1.65)1.19 (0.88 to 1.61)1.05 (0.76 to 1.44)1.01 (0.73 to 1.40)
 Functional limitations (continuous)1.08 (1.03 to 1.14)1.10 (1.00 to 1.21)0.99 (0.93 to 1.05)1.17 (1.05 to 1.31)
Model 4
 African-American1.17 (0.87 to 1.59)1.21 (0.90 to 1.63)1.08 (0.78 to 1.50)1.04 (0.75 to 1.43)
 Functional limitations (≥1 vs 0)1.47 (1.13 to 1.91)1.17 (0.92 to 1.50)0.75 (0.56 to 0.98)1.26 (0.94 to 1.69)
  • *Models were stratified by age at breast cancer diagnosis and additionally adjusted for stage of comorbidity, breast cancer, treatment, body mass index, financial adequacy, education, smoking, positive lymph node involvement, tumour size at diagnosis and period of study entry.