Table 5

The performance of the different criteria in patients in sustained remission

Percentage in sustained remissionPercentage not in sustained remissionSensitivitySpecificityPPVNPVp ValueLikelihood ratio (95% CI)
DAS28 Cr62450.190.900.620.550.0151.82 (1.11 to 2.97)
DAS28-3 Cr63450.160.910.630.530.0221.77 (1.04 to 3.02)
Boolean Cr62470.050.980.690.530.112.47 (0.77 to 7.91)
Boolean-3 Cr55470.120.910.550.530.321.33 (0.75 to 2.38)
SDAI Cr74470.080.970.740.530.0252.96 (1.09 to 8.05)
SDAI-4 Cr60470.110.930.600.530.141.62 (0.8 to 3.09)
  • Sensitivity, specificity, PPV (positive predictive value), NPV (negative predictive value) and positive likelihood ratios, all with absence of radiographic progression from baseline to 8 years as outcome.

  • *Non-progressors—patients without radiographic progression from baseline to 8 years.

  • DAS28, disease activity score calculated on 28 joints; SDAI Cr, Simplified Disease Activity Index less than 3.3 remission criterion.