Table 3

Factors predicting mortality

VariableUnivariate analysisMultivariate analysis
HR95% CIHR95% CI
Demographics
 Age ≤50 years0.64(0.35 to 1.18)
 Male gender0.67(0.36 to 1.22)
 African-American race1.46(0.80 to 2.67)
Comorbid conditions
 BMI <300.84(0.46 to 1.54)
 Comorbid conditions (≥3)1.10(0.34 to 3.57)
 Psychiatric* (n=74)0.51(0.24 to 1.09)
 Hypertension (n=68)1.24(0.66 to 2.33)
 Diabetes (n=40)2.14(1.12 to 4.08)
Disease-related
 Genotype 1 infection1.47(0.70 to 3.09)
 Cirrhosis4.78(2.55 to 8.95)3.42(1.77 to 6.61)
 Albumin <3.5 g/dL6.17(3.30 to 11.56)3.11(1.57 to 6.18)
 WCC <6600/µL1.88(1.00 to 3.52)
 Platelet count ≥150000/µL0.27(0.15 to 0.49)
 New referral0.55(0.30 to 1.02)
Treatment-related
 SVR0.08(0.02 to 0.34)0.11(0.03 to 0.47)
  • *Depression or bipolar disorder.

  • BMI, body mass index; SVR, sustained virological response; WCC, white cell count.