Patients’ clinical and echocardiographic characteristics and cardiac catheterisation data
| Preserved LV function (n=53) | Impaired LV function (n=49) | p Value | |
|---|---|---|---|
| Age (year) | 67.8±11.4 | 68 2±13.5 | 0.87 |
| Male, n (%) | 35 (66) | 32 (65) | 0.95 |
| Weight (kg) | 60.6±12.5 | 58.3±12.7 | 0.35 |
| Height (cm) | 160±10 | 159±11 | 0.76 |
| Body mass index (kg/m2) | 23.7±3.63 | 22.9±3.99 | 0.77 |
| Systolic blood pressure (mm Hg) | 126.5±15.4 | 120.5±20.9 | 0.095 |
| Diastolic blood pressure (mm Hg) | 72.9±10.2 | 66.7±13.6 | 0.010 |
| Diabetes mellitus, n (%) | 19 (36) | 25 (51) | 0.12 |
| Hypertension, n (%) | 34 (64) | 25 (51) | 0.18 |
| Dyslipidaemia, n (%) | 37 (70) | 25 (51) | 0.052 |
| Coronary artery disease, n (%) | 40 (75) | 31 (63) | 0.18 |
| ARBs or ACEIs, n (%) | 38 (72) | 28 (57) | 0.12 |
| β-Blockers, n (%) | 17 (32) | 31 (63) | 0.002 |
| Statins, n (%) | 26 (49) | 23 (47) | 0.83 |
| Calcium channel blockers, n (%) | 20 (38) | 17 (35) | 0.10 |
| Diuretics, n (%) | 13 (25) | 33 (67) | p<0.001 |
| Blood sugar (mg/dL) | 108.3±23.0 | 120.4±33.6 | 0.035 |
| Glycated haemoglobin HbA1c (%) | 6.07±1.27 | 6.13±1.17 | 0.79 |
| Immunoreactive insulin (µU/mL) | 8.84±8.22 | 11.3±20.3 | 0.42 |
| HOMA-IR | 2.39±2.44 | 3.44±5.80 | 0.23 |
| Estimated GFR (mL/min/1.73 m2) | 69.7±17.4 | 54.4±28.7 | 0.001 |
| C reactive protein (mg/dL) | 0.69±2.26 | 2.41±4.53 | 0.015 |
| GLP-1 (pmol/L) | 2.72±1.56 | 5.71±1.95 | p<0.001 |
| Brain natriuretic peptide (pg/mL) | 118±186 | 607±611 | p<0.001 |
| LVEDVI (mL/m2) | 81.8±22.2 | 124.1±50.9 | p<0.001 |
| LVESVI (mL/m2) | 26.4±12.9 | 71.8±43.0 | p<0.001 |
| Cardiac index (L/min/m2) | 3.99±1.16 | 3.73±1.36 | 0.34 |
| LVEF (%) | 62.0±4.47 | 41.7±10.2 | p<0.001 |
| E/A | 0.77±0.19 | 0.78±0.30 | 0.24 |
Data are presented as the number (%) of patients or the mean±SD.
ARBs, angiotensin II receptor blockers; E/A, the ratio of mitral inflow E-wave to A-wave velocity; GFR, glomerular filtration rate; GLP-1, glucagon-like peptide-1; LVEDVI, left ventricular end-diastolic volume index; LVEF, left ventricular ejection fraction; LVESVI, left ventricular end-systolic volume index.