Table 4

Number of psychosocial stressors in 1968 in relation to incidence of dementia over 38 years

Cases
n (%)
Model 1Model 2Model 3Model 4
All-type dementia153 (19.1)1.15 (1.05 to 1.27)1.16 (1.04 to 1.30)1.10 (1.00 to 1.25)1.13 (1.01 to 1.26)
Vascular dementia35 (4.4)0.94 (0.75 to 1.19)0.97 (0.75 to 1.26)0.79 (0.57 to 1.10)0.93 (0.71 to 1.22)
Alzheimer's disease104 (13.0)1.21 (1.08 to 1.36)1.21 (1.06 to 1.38)1.16 (1.00 to 1.35)1.17 (1.02 to 1.33)
  • Cox regression analyses presented as HRs with 95% CIs; model 1 adjust for age; model 2 adjust for age, education, socioeconomic status, marital status, work status at baseline (in 1968), and hypertension, CHD, stroke, diabetes mellitus, high waist-to-hip ratio, smoking, and wine consumption (in 1968–1980) and model 3 adjust for age and psychiatric family history (mental illness in mother, father and/or sibling is not included in number psychosocial stressors), and; model 4 adjust for age and long-standing distress (in 1968–1980).