Table 3

Treatment for RA at final visit† or AE onset‡

Total N=51Non-AE group§ N=40 (78%)AE group¶ N=11 (22%)p Value
Treatment, yes37 (73)27(68)10 (91)0.12
Corticosteroid29 (57)22 (55)7 (64)0.61
Immunosuppressant except for MTX17 (33)14 (35)3 (27)0.63
MTX10 (20)4 (10)6 (55)0.001*
Other drugs17 (33)13 (33)4 (36)0.81
  • Data are presented as n (%) and compared between non-AE group and AE group using Fisher's exact test.

  • Immunosuppressant except for MTX included azathioprine (n=1), cycrophosphaminde (n=1), etanercept (n=2), mizoribine (n=7) and tacrolimus (n=6).

  • Other drugs included actarit (n=2), bucillamine (n=5), meloxicam (n=1) and salazosulfapyridine (n=11).

  • *p<0.05.

  • †In non-AE group.

  • ‡In AE group.

  • §Non-AE group, patients who did not develop AE during the observation period.

  • ¶AE group, patients who developed AE during observation period.

  • AE, acute exacerbation; ILD, interstitial lung disease; MTX, methotrexate; RA, rheumatoid arthritis.