Table 4

Multimorbidity transitions across A&E episodes and hospital admissions and associated costs over 3 years

Study groups3-year AE £ costs
Mean (SD)
Adjusted-regression*
estimates £ (SE)
p Value3-year IP £ costs
Mean (SD)
Adjusted-regression*
estimates £ (SE)
p Value
HT+ DM−55 (132)01647 (4085)0
DM+ HT−69 (162)20 (2)<0.0012061 (4490)595 (68)<0.001
HT and DM69 (152)14 (2)<0.0012289 (4585)607 (48)<0.001
DM+ CHD−57 (124)01825 (3977)0
CHD+ DM−84 (175)22 (2)<0.0012512 (5825)431 (73)<0.001
DM and CHD104 (219)42 (3)<0.0013372 (5789)1270 (101)<0.001
DM+ CKD−60 (143)01850 (3996)0
CKD+ DM−80 (144)4 (2)0.142559 (4380)403 (73)<0.001
DM and CKD105 (190)30 (3)<0.0013642 (6063)1480 (97)<0.001
COPD+ CHD−96 (214)02642 (4814)0
CHD+ COPD−81 (180)−13 (4)<0.0012537 (5812)−152 (92)0.097
COPD and CHD138 (219)40 (5)<0.0013992 (5775)1158 (151)<0.001
COPD+ CHF−100 (211)02769 (4925)0
CHF+ COPD−120 (192)17 (5)<0.0013877 (5732)904 (125)<0.001
CHF and COPD166 (242)64 (8)<0.0014901 (6199)1954 (206)<0.001
CHF+ CKD−108 (176)03282 (4880)0
CKD+ CHF−75 (139)−31 (4)<0.0012477 (4404)−629 (114)<0.001
CKD and CHF164 (238)52 (5)<0.0015344 (6907)2116 (163)<0.001
  • *Adjusted for age, gender and deprivation as measured by the Index of Multiple deprivation.

  • A&E, accident and emergency; CHD, coronary heart disease; CHF, chronic heart failure; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; DM, diabetes mellitus; HT, hypertension.