Table 2

Change in median pain VAS scores, DAS and HAQ scores (95% CI) over 1 year

Baseline6 month1 yearChange at 6 monthsp ValueChange at 1 yearp Value
Pain score55 (48 to 62)37.9 (31.7 to 44.1)24.2 (17.7 to 30.6)−21.9 (−30.8 to −13)<0.001−27.4 (−35.6 to −19.1)<0.001
DAS4v4.5 (4.1 to 4.8)3.4 (3.1 to 3.7)3.2 (2.9 to 3.4)−1.3 (−1.8 to −0.8)<0.001−1.5 (−2 to −1.1)<0.001
mHAQ0.6 (0.5 to 0.8)0.44 (0.3 to 0.6)0.3 (0.2 to 0.4)−0.3 (−0.5 to −0.1)0.003−0.3 (−0.4 to −0.2)<0.001
Proportion of patients with
 DAS≤2.612 (14.8%)25 (25%)29 (29%)
 DAS≤3.218 (22%)48 (48%)52 (52%)