Secondary determination of role of
-
Diet -
Physical activity -
Adiposity -
Sleep -
Stress -
Built environment That impacts circulating cytokine levels, gene expression and DNA methylation patterns of TLR and cytokine genes in obese survivors of childhood brain tumours and comparing them with non-obese tumour survivors and lean and obese patients with no history of tumours | Understand the role of
-
Diet -
Physical activity -
Adiposity -
Sleep -
Stress -
Built environment On development of inflammation in obese survivors of childhood cancer and comparing them with non-obese tumour survivors and lean and obese patients with no history of tumours |
-
Age -
Sex -
Ethnicity -
Puberty -
Physical activity -
Tumour type -
Tumour location -
Tumour treatment -
Hormonal deficiencies -
BMI -
Lipid levels -
HOMA-IR
|
Obese survivors of childhood brain tumours have higher inflammatory status and altered gene methylation patterns, and this is mediated via individual and lifestyle factors |
Descriptive analysis
Regression |