Table 3

Mean (SD) SF12 Physical Component Score (PCS) and median (IQR) Mental Component Score (MCS) at baseline and 6-month follow-up and difference between the two assessment points for each arm, prescribing, review and treatment as usual (TAU)

 PrescribingReviewTAU
N*Mean (SD)N*Mean (SD)N*Mean (SD)p Value (between groups†)
Baseline SF-12 PCS4133.5 (10.8)4332.59 (11.38)4529.60 (9.71)
6-month follow-up SF12 PCS35.3 (10.8)34.62 (11.26)32.59 (9.14)
Difference SF-12 PCS1.8 (7.5)2.02 (7.56)2.99 (8.11)
p (within groups‡)0.120.090.020.75
Effect size (r)0.240.260.35
Median (IQR)Median (IQR)Median (IQR)
Baseline SF-12 MCS4252.4 (42.0;58.8)4347.9 (38.5;59.9)4551.5 (41.3;60.7)
6-month follow-up SF-12 MCS49.6 (42.8;58.1)47.9 (38.9;56.2)44.7 (37.6;55.8)
Difference SF-12 MCS−0.4 (−3.7;6.0)−1.2 (−6.6;4.2)−3.0 (−10.0;1.3)
p (within groups‡)0.640.370.0020.04
Effect size (r)0.070.140.46
  • Within-arm and between-arm p values are also reported.

  • *Number of participants in each group who completed the appropriate part of the SF-12 at both baseline and follow-up.

  • †From analysis of variance on mean difference or Kruskall-Wallis test on median difference as appropriate.

  • ‡From paired t test or Wilcoxon signed rank test as appropriate.