Table 3

Adjusted HRs for migraine predicting depression, adjusting for various stressors, age and sex

Model 1 (n=7339)Model 2 (n=7339)Model 3 (n=6840)Model 4 (n=7121)Model 5 (n=7176)Model 6 (n=7144)Model 7 (n=7127)Model 8 (n=7339)Model 9 (n=6387)
Migraine
 Yes1.84 (1.38–2.45)1.55 (1.15–2.08)1.43 (1.06–1.92)1.46 (1.08–1.98)1.54 (1.14–2.08)1.51 (1.11–2.05)1.33 (0.98–1.79)1.46 (1.07–1.99)1.19 (0.86–1.66)
 NoReferenceReferenceReferenceReferenceReferenceReferenceReferenceReferenceReference
Childhood trauma
 NoneReferenceReference
 11.23 (0.92–1.64)1.14 (0.84–1.55)
 2+2.36 (1.79–3.12)1.89 (1.38–2.59)
Recent marital status change
 Yes0.91 (0.40–2.06)0.78 (0.33–1.84)
 NoReferenceReference
Recent Unemployed
 Yes1.52 (0.93–2.49)1.16 (0.68–1.99)
 NoReferenceReference
Work stress
 1st QuartileReferenceReference
 2nd Quartile0.64 (0.48–0.85)0.70 (0.52–0.95)
 3rd Quartile0.69 (0.50–0.94)0.76 (0.55–1.06)
 4th Quartile1.12 (0.84–1.51)1.06 (0.77–1.48)
Chronic stress
 1st QuartileReferenceReference
 2nd Quartile1.45 (1.06–2.00)1.47 (1.03–2.08)
 3rd Quartile2.02 (1.50–2.73)1.89 (1.37–2.62)
 4th Quartile2.93 (2.20–3.88)2.49 (1.80–3.44)
Change in social support
 Yes0.91 (0.69–1.20)0.94 (0.71–1.23)
 NoReferenceReference
Sex
 MaleReferenceReferenceReferenceReferenceReferenceReferenceReferenceReference
 Female1.91 (1.52–2.39)1.86 (1.49–2.34)1.94 (1.55–2.44)1.92 (1.53–2.41)1.80 (1.43–2.27)1.89 (1.50–2.37)1.89 (1.50–2.39)1.83 (1.43–2.34)
Age (continuous)0.98 (0.97–0.99)0.98 (0.97–0.99)0.98 (0.97–0.99)0.98 (0.97–0.99)0.98 (0.97–0.99)0.98 (0.97–0.99)0.98 (0.97–0.99)0.98 (0.97–0.99)