Table 2

Adjusted HRs for depression predicting migraine, adjusting for various stressors, age and sex

Model 1 (n=7076)Model 2 (n=7076)Model 3 (n=6678)Model 4 (n=6868)Model 5 (n=6953)Model 6 (n=7064)Model 7 (n=7044)Model 8 (n=7076)Model 9 (n=6339)
Depression
 Yes1.85 (1.20–2.85)1.62 (1.03–2.53)1.59 (1.03–2.46)1.56 (0.98–2.47)1.61 (1.02–2.53)1.52 (0.97–2.38)1.34 (0.84–2.13)1.61 (1.02–2.54)1.30 (0.80–2.10)
 NoReferenceReferenceReferenceReferenceReferenceReferenceReferenceReferenceReference
Childhood trauma
 NoneReferenceReference
 10.95 (0.66–1.37)0.90 (0.60–1.33)
 2+1.34 (1.00–1.79)1.09 (0.79–1.51)
Recent marital status change
 Yes1.54 (0.82–2.90)1.28 (0.59–2.75)
 NoReferenceReference
Recent unemployment
 Yes1.00 (0.44–2.30)0.72 (0.29–1.78)
 NoReferenceReference
Work stress
 1st QuartileReferenceReference
 2nd Quartile0.63 (0.42–0.95)0.61 (0.39–0.95)
 3rd Quartile0.66 (0.45–0.96)0.63 (0.41–0.96)
 4th Quartile0.89 (0.61–1.31)0.81 (0.52–1.27)
Chronic stress
 1st QuartileReferenceReference
 2nd Quartile0.91 (0.59–1.40)0.99 (0.63–1.56)
 3rd Quartile1.58 (1.11–2.25)1.64 (1.12–2.41)
 4th Quartile1.76 (1.22–2.53)1.68 (1.08–2.61)
Change in social support
 Yes0.77 (0.54–1.11)0.84 (0.58–1.21)
 NoReferenceRefererence
Sex
 MaleReferenceReferenceReferenceReferenceReferenceReferenceReferenceReference
 Female2.39 (1.83–3.12)2.34 (1.79–3.08)2.49 (1.90–3.26)2.44 (1.86–3.20)2.28 (1.73–2.99)2.39 (1.83–3.12)2.48 (1.89–3.25)2.32 (1.73–3.11)
Age (continuous)0.98 (0.97–0.99)0.98 (0.97–0.99)0.98 (0.97–0.99)0.98 (0.97–0.99)0.98 (0.97–0.99)0.98 (0.97–0.99)0.98 (0.97–0.99)0.98 (0.97–0.99)