Expression of ICAM-1 (normalised ICAM/18s) and proinflammatory and anti-inflammatory cytokines by fresh human aortic endothelial cells after incubation for 48 h in medium supplemented with cadmium at two concentrations in comparison with controls (mean±SEM)
| Controls n=12 | Cadmium (100 µg/l) n=10 | Cadmium (500 µg/l) n=10 | |
|---|---|---|---|
| ICAM-1 | 0.91±0.37 | 0.63±0.19 | 0.83±0.19 |
| Granulocyte-macrophage colony-stimulating factor | 19.9±8.7 | 15.7±6.1 | 12.8±3.0 |
| Interferon-γ | 34.1±9.6 | 30.0±6.6 | 29.1±5.8 |
| Interleukin-10 | 5.1±0.78 | 5.0±1.1 | 5.5±2.1 |
| Interleukin 12 p70 | 8.2±1.8 | 7.0±0.87 | 7.6±1.48 |
| Interleukin-1β | 4.1±0.94 | 4.8±1.6 | 4.2±1.0 |
| Interleukin-2 | 22.8±12.0 | 23.0±18.4 | 15.4±5.6 |
| Interleukin-6 | 419±35 | 422±43 | 385±54 |
| Interleukin-8 | 3204±269 | 3181±480 | 2862±354 |
| Tumor necrosis factor-α | 11.1±2.1 | 10.1±1.3 | 9.3±0.87 |
ICAM-1, proatherogenic intercellular adhesion molecule-1.