Table 3

Rate estimate comparison (using margins, dydx) for birth year band trend over the different case-status groups

Birth year bandCase-statusRate estimate difference95% CIp Value
1983–1986AffectedBaseline for affected status rate estimate
No ASD no IDBaseline for no ASD no ID rate estimate
1986–1990Affected0.5730.4450.701<0.001
No ASD no ID−0.046−0.053−0.039<0.001
1990–1994Affected0.0560.0100.1020.017
No ASD no ID−0.266−0.8110.2780.338
1994–1999Affected0.0750.0280.1220.002
No ASD no ID0.263−0.3880.9130.429
1983–1986All other groupsBaseline for all other groups rate estimate
Mild ID no ASDBaseline for mild ID no ASD rate estimate
1986–1990All other groups−0.014−0.023−0.0050.001
Mild ID no ASD−0.210−0.328−0.0910.001
1990–1994All other groups0.0420.0320.052<0.001
Mild ID no ASD−0.332−0.452−0.212<0.001
1994–1999All other groups0.0810.0700.091<0.001
Mild ID no ASD0.084−0.0560.2240.239
1983–1986All other groupsBaseline for all other groups rate estimate
Severe ID no ASDBaseline for severe ID no ASD rate estimate
1986–1990All other groups−0.035−0.043−0.026<0.001
Severe ID no ASD3.5702.9054.236<0.001
1990–1994All other groups−0.001−0.0100.0090.841
Severe ID no ASD7.9017.0428.760<0.001
1994–1999All other groups0.0400.0300.050<0.001
Severe ID no ASD9.3998.31210.487<0.001
1983–1986All other groupsBaseline for all other groups rate estimate
ASD & IDBaseline for ASD & ID rate estimate
1986–1990All other groups−0.021−0.030−0.012<0.001
ASD & ID1.4881.1151.862<0.001
1990–1994All other groups0.0460.0340.057<0.001
ASD & ID0.8550.4671.242<0.001
1994–1999All other groups0.0790.0680.090<0.001
ASD & ID0.8350.5021.168<0.001
1983–1986All other groupsBaseline for all other groups rate estimate
ASD no IDBaseline for ASD & no ID rate estimate
1986–1990All other groups−0.016−0.025−0.008<0.001
ASD no ID0.104−0.3210.5300.631
1990–1994All other groups0.0480.0360.059<0.001
ASD no ID0.4930.0570.9290.027
1994–1999All other groups0.0820.0710.093<0.001
ASD no ID−0.064−0.4630.3350.754
1983–1986All other groupsBaseline for all other groups rate estimate
Biomedical IDBaseline for biomedical ID rate estimate
1986–1990All other groups−0.031−0.039−0.023<0.001
Biomedical ID1.4391.1001.777<0.001
1990–1994All other groups−0.005−0.0150.0050.340
Biomedical ID5.3074.8285.786<0.001
1994–1999All other groups0.0550.0440.065<0.001
Biomedical ID2.7312.3223.140<0.001
  • ASD, autism spectrum disorder; ID, intellectual disability.