Baseline characteristics of subjects who remained NGT, developed isolated IFG and IGT in the longitudinal study.
| NGT | Isolated IFG | IGT | p Value | |
|---|---|---|---|---|
| Number of subjects | 458 | 44 | 58 | |
| Current smokers (%) | 48 | 30* | 50 | 0.05 |
| Age (years) | 49.3±5.7 | 50.2±4.4 | 50.5±4.9 | 0.14 |
| Height (cm) | 169.9±5.6 | 170.2±4.9 | 167.1±6.7** | 0.01 |
| BMI (kg/m2) | 23.0±2.5 | 23.8±2.3* | 23.7±3.0* | 0.04 |
| Systolic BP (mm Hg) | 125.4±16.7 | 130.5±16.9* | 129.3±14.5 | 0.048 |
| Pack-year smoking | 29.9±15.6 | 31.1±12.1 | 30.1±18.5 | 0.97 |
| FEV1/FVC (%) | 80.1±7.1 | 79.7±6.3 | 79.9±7.9 | 0.95 |
| %FVC (%) | 97.5±14.2 | 93.0±14.7* | 90.0±16.0*** | <0.001 |
| Fasting glucose (mmol/l) | 5.3±0.4 | 5.6±0.2*** | 5.5±0.3** | <0.001 |
| 120 min glucose (mmol/l) | 5.6±0.9 | 6.0±1.2 | 6.4±0.9*** | <0.001 |
| HbA1c (%) | 5.07±0.33 | 5.31±0.37*** | 5.19±0.30* | <0.001 |
| HOMA-R | 1.04±0.53 | 1.19±0.61 | 1.31±0.64** | 0.001 |
| C reactive protein (mg/l) | 0.10±0.23 | 0.18±0.42 | 0.16±0.30 | 0.26 |
| T-chol (mg/dl) | 201.4±34.5 | 205.3±27.1 | 212.5±28.6* | 0.05 |
| Duration (month) | 28.6±6.2 | 28.5±5.1 | 27.6±5.6 | 0.13 |
Values are number, percentage (%) or mean±SD.
*p < 0.05.
**p<0.01.
***p<0.001 vs NGT.
BMI, body mass index; BP, blood pressure; CRP, C reactive protein; HOMA-R, homeostasis model assessment of insulin resistance; IFG, increased fasting glucose; IGT, impaired glucose tolerance; NGT, normal glucose tolerance; T-chol, total cholesterol.