Table 3

Specification of infants exposed to SSRI and benzodiazepines and with a relatively severe malformation

NumberMalformationSSRIBenzodiazepineOther drugs reported
1HypospadiasCitalopramAlprazolam
2HypospadiasFluoxetineAlprazolamPropranolol
3Hypospadias+VSDParoxetineLorazepamParacetamol
4VSD+ASDSertralineAlprazolamASA+prometazine
5VSD+ASDEscitalopramOxazepamHydroxyzine
6Pulmonary valve stenosisCitalopramAlprazolamZolpidem
7Pulmonary valve stenosisParoxetineOxazepam
8Laryngeal malformationFluoxetineAlprazolamBuspirone, B12
9PylorostenosisSertralineAlprazolamMeclozine
10Duodenal atresia/stenosisCitalopramOxazepam
11Anorectal fistuleSertralineAprazolam
12MegacolonFluoxetineAprazolam
13Pes equino-varusCitalopramOxazepam
14Polydactyly handSertralineDiazepamRanitidine
15Down syndromeCitalopramAlprazolam
16Down syndromeEscitalopramOxazepamThyroxine, disulfiram
  • ASA, acetyl salicylic acid; ASD, atrium septum defect; VSD, ventricular septum defect.