Rest and stress haemodynamics
| Haemodynamics | Normal diastolic function (N=102) | Stage 1 DD (N=243) | Stage ≥ 2DD (N=150) | p Value |
|---|---|---|---|---|
| Bruce protocols | 22 (22%) | 20 (8%) | 11 (7%) | <0.0001 |
| Rest HR, mean (SD) (bpm) | 65 (10) | 66 (11) | 64 (11) | 0.20 |
| SBP, mean (SD) (mm Hg) | 122 (15) | 128 (20) | 120 (19) | <0.0001 |
| DBP, mean (SD) (mm Hg) | 79 (12) | 81 (10) | 76 (11) | <0.0001 |
| Max HR, mean (SD) (bpm) | 148 (25) | 131 (24) | 131 (27) | <0.0001 |
| Peak SBP, mean (SD) (mm Hg) | 157 (30) | 166 (33) | 149 (32) | <0.0001 |
| Peak DBP, mean (SD) (mm Hg) | 82 (12) | 85 (12) | 79 (13) | <0.0001 |
| HRR, mean (SD) (bpm) | 32 (10) | 26 (12) | 25 (13) | <0.0001 |
| Hypotension | 12 (12%) | 26 (11%) | 14 (9%) | 0.82 |
| Duke treadmill score | 0.006 | |||
| Normal | 35 (34%) | 67 (28%) | 24 (16%) | |
| Abnormal | 17 (17%) | 56 (23%) | 26 (17%) | |
| Uninterpretable due to abnormal baseline ST | 50 (49%) | 120 (49%) | 10 (67%) | |
| METs achieved | 7.7 (2.3) | 6.3 (2.0) | 6.2 (2.4) | <0.0001 |
| METs≥7 | 60 (59%) | 76 (31%) | 47 (31%) | <0.0001 |
DBP, diastolic blood pressure; DD, diastolic dysfunction; HR, heart rate; HRR, heart rate recovery; Max, (maximal; MET, metabolic equivalent; SBP, systolic blood pressure.