Patient baseline characteristics
| All patients (N=100) | Patients with AC (N=75) | Patients with SCC (N=25) | p Value* | |
|---|---|---|---|---|
| Age, mean±SD—years | 64.2±11.6 | 63.9±11.0 | 65.2±13.5 | 0.63 |
| Sex—no. (%) | <0.0005 | |||
| Female | 21 (21) | 9 (12) | 12 (48) | |
| Male | 79 (79) | 66 (88) | 13 (52) | |
| Race—no. (%) | 0.13 | |||
| White | 80 (80) | 62 (84) | 18 (72) | |
| Asian | 4 (4) | 1 (1) | 3 (12) | |
| Black | 3 (3) | 2 (3) | 1 (4) | |
| Missing | 13 (13) | 10 (13) | 3 (12) | |
| Ethnicity—no. (%) | 0.48 | |||
| Non-Hispanic | 90 (90) | 66 (88) | 24 (96) | |
| Hispanic | 2 (2) | 2 (3) | 0 | |
| Missing | 8 (8) | 7 (9) | 1 (4) | |
| Location of tumour†—no. (%) | <0.0005 | |||
| Upper oesophagus | 5 (5) | 0 | 5 (20) | |
| Middle oesophagus | 9 (9) | 2 (3) | 7 (28) | |
| Lower oesophagus | 31 (31) | 20 (27) | 11 (44) | |
| Gastro-oesophageal junction | 55 (55) | 53 (71) | 2 (8) | |
| Presence of Barrett's oesophagus—no. (%) | 46 (46) | 46 (61) | 0 | <0.0005 |
| Yes | 54 (54) | 29 (39) | 25 (100) | |
| No | ||||
| Pathological stage—no. (%) | 0.06 | |||
| I | 30 (30) | 27 (36) | 3 (12) | |
| II | 31 (31) | 23 (31) | 8 (32) | |
| III | 37 (37) | 23 (31) | 14 (56) | |
| IV | 2 (2) | 2 (3) | 0 | |
| Histological grade—no. (%) | 0.10 | |||
| 1 (Well-differentiated) | 11 | 11 | 0 | |
| 2 (Moderately differentiated) | 41 | 30 | 11 | |
| 3 (Poorly differentiated) | 44 | 30 | 14 | |
| 4 (Undifferentiated) | 4 | 4 | 0 | |
| Neoadjuvant therapy | 0.04 | |||
| Yes | 28 (28) | 25 (33) | 3 (12) | |
| No | 72 (72) | 50 (67) | 22 (88) |
*p Values were calculated using the t test for continuous variables and the χ2 test for categorical variables.
†Location of tumour was recorded as the most superior location of the tumour in the oesophagus. For example, if the pathology report noted tumour at the upper and middle oesophagus, the location was recorded as upper oesophagus.
AC, adenocarcinoma; SCC, squamous cell carcinoma.