Table 4

Multivariable analysis of risk factors for common cancers among New South Wales opioid substitution therapy registrants, 1993–2007

Lung cancerNon-Hodgkin's lymphomaLiver cancer
nIRR*95% CIp ValuenIRR*95% CIp ValuenIRR*95% CIp Value
Current age†271.191.15–1.24<0.0001231.061.01–1.110.025131.201.13–1.27<0.0001
Calendar year†270.910.81–1.030.131231.161.01–1.370.054131.130.91–1.490.317
Sex
 Men221.550.63–4.650.378171.030.42–2.900.954123.940.76–72.20.190
 Women (ref)51.0061.0011.00
Notified HCV infection
 Yes213.291.39–9.070.011131.120.49–2.650.792129.051.73–1660.036
 No (ref)61.00101.0011.00
Notified HBV infection‡
 Yes21.590.25–5.420.531034.631.03–15.40.021
 No (ref)251.0023101.00
Notified HIV infection‡
 Yes0426.07.40–71.3<0.00010-
 No (ref)27191.0013
  • HBV, hepatitis B virus; HCV, hepatitis C virus; IRR, incidence rate ratio; ref, reference group in analysis.

  • *Adjusted for current age (years), calendar year, sex and time-dependent HCV notification status, HBV notification status and HIV notification status.

  • †IRR refers to 1 year increase.

  • ‡IRRs could not be calculated if a cancer case did not occur in one of the binary groupings.

  • Note: Infection groupings are not mutually exclusive.