Multiple linear regression results of selected factors affecting change in MMSE in women followed from 2000 to 2005
| Factor | B | 95% CI | p |
|---|---|---|---|
| ASA use at baseline | 0.75 | (0.01 to 1.49) | 0.046 |
| MMSE at baseline | −0.37 | (−0.54 to −0.21) | <0.001 |
| Age at baseline | −0.12 | (−0.17 to − 0.06) | <0.001 |
| GCVD score | 0.01 | (−0.03 to 0.04) | 0.795 |
| Additional factors* | |||
| Only mandatory education | 0.44 | (−1.11 to 0.99) | 0.118 |
| NSAID | 0.07 | (−0.65 to 0.78) | 0.852 |
| APOE ɛ4 | −0.25 | (−0.86 to 0.37) | 0.431 |
APOE, apolipoprotein E; ASA, acetylsalicylic acid; GCVD, general cardiovascular disease (Framingham Heart Study); MMSE, Mini Mental State Examination; NSAIDs, non-steroidal anti-inflammatory drugs.
*Each additional factor was added to the model separately.