Table 2

Multiple linear regression results of selected factors affecting change in MMSE in women followed from 2000 to 2005

FactorB95% CIp
ASA use at baseline0.75(0.01 to 1.49)0.046
MMSE at baseline−0.37(−0.54 to −0.21)<0.001
Age at baseline−0.12(−0.17 to − 0.06)<0.001
GCVD score0.01(−0.03 to 0.04)0.795
Additional factors*
 Only mandatory education0.44(−1.11 to 0.99)0.118
 NSAID0.07(−0.65 to 0.78)0.852
APOE ɛ4−0.25(−0.86 to 0.37)0.431
  • APOE, apolipoprotein E; ASA, acetylsalicylic acid; GCVD, general cardiovascular disease (Framingham Heart Study); MMSE, Mini Mental State Examination; NSAIDs, non-steroidal anti-inflammatory drugs.

  • *Each additional factor was added to the model separately.