Table 2

CFS/ME referrals, assessments and diagnoses by year and by quartiles of PCT-level measures of social deprivation and health inequality

	Referrals*	Assessments*	Diagnoses*
	Mean (95% CI)	Mean (95% CI)	Mean (95% CI)
Rate per 1000 adults*
Year
2008	0.34 (0.29 to 0.41)	0.29 (0.24 to 0.35)	0.25 (0.19 to 0.33)
2009	0.31 (0.26 to 0.37)	0.28 (0.23 to 0.34)	0.22 (0.17 to 0.29)
2010	0.31 (0.26 to 0.36)	0.27 (0.22 to 0.32)	0.22 (0.17 to 0.28)

Rate ratio (95% CI) per year^†	0.95 (0.84 to 1.07)	0.96 (0.84 to 1.09)	0.93 (0.77 to 1.12)
	P_trend=0.39	P_trend=0.49	P_trend=0.45
Rate per 1000 adults per year*
Index of Multiple Deprivation (IMD)
First quartile (least deprived)	0.29 (0.22 to 0.37)	0.25 (0.18 to 0.33)	0.19 (0.12 to 0.30)
Second quartile	0.32 (0.24 to 0.42)	0.27 (0.20 to 0.36)	0.24 (0.15 to 0.38)
Third quartile	0.30 (0.22 to 0.40)	0.26 (0.19 to 0.36)	0.22 (0.14 to 0.34)
Fourth quartile (most deprived)	0.32 (0.23 to 0.43)	0.32 (0.24 to 0.43)	0.24 (0.16 to 0.38)
Rate ratio (95% CI) per IMD quartile^†	1.00 (0.88 to 1.15)	1.06 (0.93 to 1.22)	1.07 (0.87 to 1.31)
	P_trend=0.97	P_trend=0.39	P_trend=0.54
Rate per 1000 adults per year*
Slope Index of Inequality (SII)
First quartile (least inequality)	0.32 (0.25 to 0.42)	0.29 (0.21 to 0.39)	0.28 (0.17 to 0.48)
Second quartile	0.32 (0.25 to 0.41)	0.26 (0.20 to 0.35)	0.18 (0.12 to 0.27)
Third quartile	0.28 (0.21 to 0.38)	0.27 (0.19 to 0.37)	0.19 (0.13 to 0.28)
Fourth quartile (most inequality)	0.29 (0.21 to 0.39)	0.27 (0.20 to 0.37)	0.28 (0.17 to 0.45)
Rate ratio (95% CI) per SII quartile^†	0.95 (0.83 to 1.09)	0.98 (0.86 to 1.13)	1.01 (0.82 to 1.25)
	P_trend=0.46	P_trend=0.83	P_trend=0.90

*Means and 95% CIs estimated from negative bionomial regression model incorporating year or quartile as categorical variable.
^†P_trend across years or quartiles as linear variable in negative bionomial regression model.
PCT, Primary Care Trust; CFS/ME, chronic fatigue syndrome or myalgic encephalomyelitis.