HRs for childhood cancer according to the Apgar score at 5 min
| Apgar score | Cases (rate per 1000) | Crude HR | Adjusted HR (95% CI) † |
|---|---|---|---|
| 0 | 3 (0.7) | 0.47 (0.15 to 1.45) | 0.56 (0.18 to 1.73) |
| 1 | 15 (2.9) | 2.44 (1.47 to 4.04)* | 2.17 (1.31 to 3.60)* |
| 2 | 6 (1.9) | 1.89 (0.61 to 3.54) | 1.72 (0.77 to 3.82) |
| 3 | 9 (2.1) | 1.85 (0.96 to 3.56) | 1.67 (0.87 to 3.21) |
| 4 | 14 (2.2) | 1.61 (0.94 to 2.78) | 1.48 (0.86 to 2.55) |
| 5 | 21 (2.1) | 1.40 (0.91 to 2.18) | 1.32 (0.85 to 2.05) |
| 0–5 combined | 68 (2.0) | 1.54 (1.21 to 1.96)* | 1.46 (1.15 to 1.89)* |
| 6 | 28 (1.5) | 1.03 (0.71 to 1.49) | 0.95 (0.66 to 1.38) |
| 7 | 61 (1.6) | 1.15 (0.99 to 1.34) | 1.00 (0.77 to 1.29) |
| 8 | 177 (1.7) | 1.18 (1.08 to 1.29) | 1.08 (0.93 to 1.26) |
| 6–8 combined | 266 (1.7) | 1.12 (0.99 to 1.27) | 1.05 (0.92 to 1.18) |
| 9–10 | 7216 (1.6) | 1.0 (ref) | 1.0 (ref) |
*p<0.05.
†Adjusted for country, sex, maternal factors at child birth (age, education and smoking during pregnancy) and birth characteristics of the child (birth weight, gestational age and birth order).