Measles case death ratio for measles-vaccinated and measles-unvaccinated cases in African prospective community studies and community surveys with long-term follow-up
Country | Period | Study; period of follow-up | Vaccinated cases, % (deaths/persons) | Unvaccinated cases, % (deaths/persons) | Mortality ratio (95% CI) |
Guinea-Bissau44 * | 1988 | PCS; 5-year follow-up | 4 (1/23) | 16 (8/46) | 0.25 (0.03–1.88) |
Guinea-Bissau34 | 1984–1987 | PCS; 2-year follow-up | 0 (0/4) | 14 (2/14) | 0 (0–20.10) |
Burundi45 † | 1988–1989 | SUR; 7-month follow-up | 3/1363 person-months | 19/2629 person-months | 0.30 (0.09–1.03) |
Senegal36 | 1987–1994 | PCS; 1-year follow-up | 0 (0/127) | 1 (15/1055) | 0 (0–2.32) |
Bissau (unpublished) | 1991–1994 | PCS; 3-year follow-up | 3 (8/319) | 9 (29/338) | 0.29 (0.14–0.63) |
Total | 0.27 (0.14–0.50) |
Sources: Reviews of measles case death studies27–31 and PubMed search for measles mortality/case death in vaccinated children; compiled by Henning Andersen shortly before he died.
↵* There were no data on acute case death in the present study since the study only included children who had a convalescent sample collected.
↵† This study did not report the acute case death but only overall mortality for the 7 months of follow-up.
PCS, prospective community studies; SUR, community surveys or outbreak investigations.