Table 2.1

Mixed treatment comparisons (MTC) and direct evidence for the oral and intravenous administered medication. Upper right quadrants indicate the number of direct comparisons available, the direct ORs and 95% CIs, lower left quadrants indicate the MTC median OR and credible regions. Beneath the table is the estimated most likely treatment to stop children from vomiting: orally administered medication

OR of the direct evidence
PlaceboGranisetronOndansetron
Median OR from the MTC
 PlaceboOR 3.13 (1.16 to 8.49)**OR 3.88 (2.6 to 5.77)***
 Granisetron3.25 (0.62 to 17.69)No data available
 Ondansetron4.33 (2.11 to 10.11)***1.33 (0.21 to 8.76)
  • **p<0.05; ***p<0.01.

  • Estimated best treatment option: ondansetron 65%, granisetron 35% and placebo 0%.