Table 1

Direct evidence of random-effects meta-analyses

AnalysisFigureOutcomeRR95% CIp ValueI2
LowerUpper
Oral ondansetron versus placebo
 1.13.1.1Cessation of vomiting1.451.201.74<0.00161%
 1.23.1.2Cessation of vomiting—excluding Yilmaz et al171.331.191.49<0.0010%
 2.14.1.1Proportion with immediate IVT during the ED0.410.290.59<0.0010%
 2.24.1.2Proportion with IVT up to 72 h (best–worst)0.570.420.76<0.0010%
 2.34.1.3Proportion with IVT up to 72 h (worst–best)0.530.390.72<0.0010%
 3.15.1.1Proportion admitted during the ED0.430.181.000.0517%
 3.25.1.2Proportion admitted up to 72 h (best–worst)0.600.341.040.0749%
 3.35.1.3Proportion admitted up to 72 h (worst–best)0.730.431.230.240%
 4.16Revisit rate1.240.493.150.6628%
Intravenous ondansetron versus placebo
 5.13.1.3Cessation of vomiting2.271.054.940.0476%
  • ED, emergency department; IVT, intravenous rehydration therapy.