Analysis | Figure | Outcome | RR | 95% CI | p Value | I2 | |
Lower | Upper | ||||||
Oral ondansetron versus placebo | |||||||
1.1 | 3.1.1 | Cessation of vomiting | 1.45 | 1.20 | 1.74 | <0.001 | 61% |
1.2 | 3.1.2 | Cessation of vomiting—excluding Yilmaz et al17 | 1.33 | 1.19 | 1.49 | <0.001 | 0% |
2.1 | 4.1.1 | Proportion with immediate IVT during the ED | 0.41 | 0.29 | 0.59 | <0.001 | 0% |
2.2 | 4.1.2 | Proportion with IVT up to 72 h (best–worst) | 0.57 | 0.42 | 0.76 | <0.001 | 0% |
2.3 | 4.1.3 | Proportion with IVT up to 72 h (worst–best) | 0.53 | 0.39 | 0.72 | <0.001 | 0% |
3.1 | 5.1.1 | Proportion admitted during the ED | 0.43 | 0.18 | 1.00 | 0.05 | 17% |
3.2 | 5.1.2 | Proportion admitted up to 72 h (best–worst) | 0.60 | 0.34 | 1.04 | 0.07 | 49% |
3.3 | 5.1.3 | Proportion admitted up to 72 h (worst–best) | 0.73 | 0.43 | 1.23 | 0.24 | 0% |
4.1 | 6 | Revisit rate | 1.24 | 0.49 | 3.15 | 0.66 | 28% |
Intravenous ondansetron versus placebo | |||||||
5.1 | 3.1.3 | Cessation of vomiting | 2.27 | 1.05 | 4.94 | 0.04 | 76% |
ED, emergency department; IVT, intravenous rehydration therapy.