Table 1

The patient outcomes measured in the trial

	Method of assessment	Outcome	Measurement tool (where appropriate)
Primary outcome	Research coordinator blinded to group allocation	Physical function	Rivermead Mobility Index 3 months postrandomisation
Secondary outcomes
Hospital	Research coordinators	Length of stay ICU readmission rate Survival to hospital discharge Weekly physical function Weekly levels of fatigue, breathlessness, appetite, pain and joint stiffness Weekly presence of delirium Weekly hand grip strength	Rivermead Mobility Index Visual analogue scores Confusion-Agitation Method for ICU Hand grip dynamometry
3 months	Research coordinator blinded to group allocation	HRQoL Levels of fatigue, breathlessness, appetite, pain and joint stiffness, patient satisfaction^*, healthcare resource use, anxiety and depression Nutritional status (subjective global assessment of nutrition), weight/BMI, hand grip strength, physical mobility, post-traumatic stress disorder symptomatology	Total, Physical Component Score and Mental Component Score SF-12 score, Visual analogue score Patient satisfaction measure, Health Economic Questionnaire, Hospital Anxiety and Depression (HAD) Questionnaire Physical component of the Subjective Global Assessment of Nutrition tool Hand grip dynamometry, 2 m timed up-and-go time, Davidson's Trauma Scale Score (DTS)
6 months	Postal questionnaires	Survival, physical function HRQoL Levels of fatigue, breathlessness; appetite; pain and joint stiffness, Healthcare resource use, Anxiety and depression Post-traumatic stress disorder symptomatology	Rivermead Mobility Index, Total, Physical Component Score, and Mental Component Score SF-12 score, Visual analogue score Health economic questionnaire, Hospital Anxiety and Depression (HAD) Questionnaire Davidson's Trauma Scale Score (DTS)
12 months	Postal questionnaires	Survival, Physical function HRQoL Levels of fatigue, breathlessness, appetite, pain and joint stiffness Healthcare resource use, anxiety and depression Post-traumatic stress disorder symptomatology	Rivermead Mobility Index, Total, Physical Component Score, and Mental Component Score SF-12 score, Visual analogue score Health Economic Questionnaire, HAD Questionnaire Davidson's Trauma Scale Score (DTS)

↵* The patient satisfaction measure used in the trial was derived based on data obtained in the pretrial work, especially the qualitative research in reference14. The tool is available on the RECOVER page of the ECTU website (http://www.clinicaltrials.ed.ac.uk).
HRQoL, health-related quality of life; ICU, intensive care unit.