Table 3

Semen quality of 4867 young men from the general population in the Copenhagen area in Denmark

Mean (SD)Median (5–95)p Values comparing
All periods2001–2005 vs 2006–20101996–2000 vs 2006–2010
Semen volume (ml)
 Investigation period 1996–20103.4 (2.0)3.2 (1.3–6.0)
  Investigation period 1996–20003.3 (1.5)3.1 (1.2–5.8)
  Investigation period 2001–20053.3 (1.4)3.2 (1.4–5.9)
  Investigation period 2006–20103.6 (3.1)3.3 (1.3–6.3)0.0040.0110.001
Sperm concentration (million/ml)
 Investigation period 1996–201060 (57)45 (3–163)
  Investigation period 1996–200058 (55)43 (3–167)
  Investigation period 2001–200560 (58)45 (3–156)
  Investigation period 2006–201062 (55)48 (3–169)0.0650.120.020
Total sperm count (million)
 Investigation period 1996–2010193 (232)143 (9–529)
  Investigation period 1996–2000185 (184)132 (6–531)
  Investigation period 2001–2005191 (241)146 (8–508)
  Investigation period 2006–2010206 (258)151 (13–559)0.0020.0150.001
Normal morphology (%)
 Investigation period 1996–20107.1 (4.9)6.5 (0.5–16.0)
  Investigation period 1996–20007.3 (5.1)7.0 (1.0–17.0)
  Investigation period 2001–20056.9 (4.8)6.0 (0.5–15.5)
  Investigation period 2006–20107.5 (4.9)7.0 (0.5–16.0)0.0160.0230.97
Total normal spermatozoa (million)
 Investigation period 1996–201016.3 (23.9)8.4 (0.0–57.4)
  Investigation period 1996–200016.5 (24.5)7.9 (0.0–60.9)
  Investigation period 2001–200515.5 (22.6)8.0 (0.0–53.8)
  Investigation period 2006–201017.9 (25.3)9.8 (0.1–59.3)0.0400.0120.076
Progressively motile (%)
 Investigation period 1996–201056 (17)59 (23–77)
  Investigation period 1996–200054 (17)57 (22–75)
  Investigation period 2001–200557 (17)60 (22–77)
  Investigation period 2006–201057 (16)59 (25–79)<0.00050.300.005
Motile (%)
 Investigation period 1996–201065 (15)68 (35–83)
  Investigation period 1996–200065 (15)68 (38–82)
  Investigation period 2001–200564 (15)67 (35–82)
  Investigation period 2006–201065 (16)68 (33–85)0.170.090.71
  • 5–95: 5–95 percentiles.

  • p Values: Obtained from regression analysis taking confounders into consideration.