Table 2

Efficacy outcomes

	Visit 2	Visit 3
Percentage change in TWSTRS score, mean ± SD	(n=374)	(n=380)
Severity subscore	–40.8±25.1	–16.5±22.3
Disability subscore	–36.3±49.8	–6.6±90.2
Pain subscore	–35.8±49.9	–7.6±72.6
Total score	–39.6±26.6	–15.4±27.0
Tremor	(n=375^†)	(n=380)
Subjects with improvement in tremor^* with treatment, n (%)	66/181^†(36.5)	41/178^* (23.0)
CDIP-58 subscales scores, mean ± SD	(n=93^‡)	–
Head and neck symptoms	26.1±21.9	–
Pain and discomfort	20.5±23.5	–
Upper limb activities	16.3±19.9	–
Walking	15.3±21.5	–
Sleep	12.3±20.0	–
Annoyance	15.6±23.9	–
Mood	13.9±20.5	–
Psychosocial functioning	19.2±23.6	–

↵* Improvement defined by presence of tremor at baseline and absence of tremor at subsequent visits.
↵† Subjects with data available at this timepoint and with tremor present at baseline.
↵‡ Questionnaire in English, thus completed by English-speaking patients only.