Subject demographics and CD characteristics (safety population)
| Demographic characteristic | Total, n=404 |
| Gender, n (%) | |
| Male | 142 (35.1) |
| Female | 262 (64.9) |
| Age (years), n (%) | |
| 18–30 | 18 (4.5) |
| 31–40 | 52 (12.9) |
| 41–50 | 105 (26.0) |
| 51–60 | 107 (26.5) |
| 61–70 | 81 (20.0) |
| >70 | 41 (10.1) |
| Body weight (kg), mean (SD) | 72.8 (14.9) |
| Duration of cervical dystonia, n (%) | |
| <6 months | 10 (2.5) |
| 6 months to <1 year | 27 (6.7) |
| 1–5 years | 140 (34.7) |
| 6–10 years | 89 (22.0) |
| 11–20 years | 84 (20.8) |
| >20 years | 54 (13.4) |
| Type of cervical dystonia, n (%) | |
| Sporadic | 383 (94.8) |
| Familial | 21 (5.2) |
| Location type, n (%) | |
| Focal | 370 (91.6) |
| Segmental | 20 (5.0) |
| Multifocal | 9 (2.2) |
| Generalised | 5 (1.2) |
| Localisation, n (%) | |
| Head/neck | 404 (100.0) |
| Trunk | 13 (3.2) |
| Upper limb | 29 (7.2) |
| Lower limb | 6 (1.5) |
| Predominant component, n (%) | |
| Rotation | 294 (72.8) |
| Laterocollis | 57 (14.1) |
| Tremor | 20 (5.0) |
| Retrocollis | 12 (3.0) |
| Shoulder elevation | 8 (2.0) |
| Anterocollis | 4 (1.0) |
| Jerk | 4 (1.0) |
| Lateral shift of column | 3 (0.7) |
| Sagittal shift of column | 2 (0.5) |
| Secondary components present, n (%) | |
| Yes | 339 (83.9) |
| Most frequent combinations of predominant and secondary components, n (%) | |
| Rotation and laterocollis | 161 (39.9) |
| Rotation and shoulder elevation | 143 (35.4) |
| Rotation and tremor | 73 (18.1) |
| TWSTRS score at baseline, mean ± SD | |
| Severity subscale | 19.5±3.8 |
| Disability subscale | 10.6±5.9 |
| Pain subscale | 6.6±4.9 |
| Total score | 36.8±10.7 |
| Baseline tremor present, n (%) | 191 (47.3) |
| CDIP-58 subscales scores*, mean ± SD | |
| Head and neck symptoms | 50.6±25.2 |
| Pain and discomfort | 31.8±27.8 |
| Upper limb activities | 26.1±24.6 |
| Walking | 22.4±26.7 |
| Sleep | 23.0±31.0 |
| Annoyance | 26.4±27.7 |
| Mood | 21.6±25.9 |
| Psychosocial | 30.7±28.2 |
↵* CDIP-58, n=99 (questionnaire in English, thus completed by English-speaking patients only).
CD, cervical dystonia.