Table 3

Distribution of selected comorbid conditions in individual collaborating cohorts and the combined cohort

ComorbiditiesCohort 1Cohort 2Cohort 3Cohort 4Cohort 5Cohort 6ICCC
COPD
 Yes569 (27.0)588 (25.7)638 (18.7)10 (1.0)1034 (32.3)2839 (20.5)
 No1541 (73.0)1687 (73.8)2777 (81.3)1004 (99.0)2167 (67.7)9176 (66.1)
 Missing/NA1847 (100)0 (0)12 (0.5)0 (0)0 (0)0 (0)1859 (13.4)
Asthma
 Yes440 (12.9)1 (0.01)441 (3.2)
 No2975 (87.1)1013 (99.9)3988 (28.7)
 Missing/NA1847 (100)2110 (100)2287 (100)0 (0)0 (0)3201 (100)9445 (68.1)
Pleural effusion
 Yes201 (10.9)219 (10.4)204 (8.9)745 (21.8)112 (11.0)461 (14.4)1942 (14.0)
 No1523 (82.5)1891 (89.6)1976 (86.4)2670 (78.2)902 (89.0)2715 (84.8)11 677 (84.2)
 Missing/NA123 (6.7)0 (0)107 (4.7)0 (0)0 (0)25 (0.8)255 (1.8)
Heart failure
 Yes294 (15.9)163 (7.7)253 (11.1)727 (21.3)121 (11.9)427 (13.3)1985 (14.3)
 No1429 (77.4)1947 (92.3)2030 (88.8)2688 (78.7)893 (88.1)2774 (86.7)11 761 (84.8)
 Missing/NA124 (6.7)0 (0)4 (0.2)0 (0)0 (0)0 (0)128 (0.9)
Coronary artery disease
 Yes215 (10.2)406 (17.8)910 (26.6)667 (20.8)2198 (15.8)
 No1895 (89.8)1880 (82.2)2505 (73.4)2534 (79.2)8814 (63.5)
 Missing/NA1847 (100)0 (0)1 (<0.1)0 (0)1014 (100)0 (0)2862 (20.6)
Cerebrovascular disease
 Yes150 (8.1)200 (9.5)210 (9.2)306 (9.0)143 (14.1)267 (8.3)1276 (9.2)
 No1574 (85.2)1910 (90.5)2076 (90.8)3109 (91.0)871 (85.9)2934 (91.7)12 474 (89.9)
 Missing123 (6.7)0 (0)1 (<0.1)0 (0)0 (0)0 (0)124 (0.9)
Liver disease
 Yes34 (1.8)76 (3.6)33 (1.4)117 (3.4)17 (1.7)28 (0.9)305 (2.2)
 No1690 (91.5)2034 (96.4)2251 (98.6)3298 (96.6)997 (98.3)3173 (99.1)13 443 (96.9)
 Missing123 (6.7)0 (0)3 (0)0 (0)0 (0)0 (0)126 (0.9)
Renal disease
 Yes89 (4.8)160 (7.6)153 (6.7)490 (14.3)106 (10.5)108 (3.4)1106 (8.0)
 No1635 (88.5)1950 (92.4)2131 (93.2)2925 (85.7)908 (89.5)3093 (96.6)12 642 (91.1)
 Missing123 (6.7)0 (0)3 (0.1)0 (0)0 (0)0 (0)126 (0.9)
Cancer
 Yes87 (4.7)131 (6.2)109 (4.8)499 (14.6)1 (0.1)85 (2.7)912 (6.6)
 No1637 (88.6)1979 (93.8)2171 (94.9)2916 (85.4)1013 (99.9)3116 (97.3)12 832 (92.5)
 Missing123 (6.7)0 (0)7 (0.3)0 (0)0 (0)0 (0)130 (0.9)
Diabetes
 Yes309 (14.6)235 (10.3)190 (5.6)625 (19.5)1359 (9.8)
 No1801 (85.4)2052 (89.7)3225 (94.4)2576 (80.5)9654 (69.6)
 Missing/NA1847 (100)0 (0)0 (0)0 (0)1014 (100)0 (0)2861 (20.6)
Dementia
 Yes276 (13.1)141 (6.2)265 (7.8)22 (2.2)128 (4.0)832 (6.0)
 No1834 (86.9)2141 (93.6)3150 (92.2)992 (97.8)3072 (96.0)11 189 (80.6)
 Missing/NA1847 (100)0 (0)5 (0.2)0 (0)0 (0)1 (<0.1)1853 (13.4)
Seizure
 Yes91 (4.0)151 (4.4)2 (0.2)244 (1.8)
 No2196 (96.0)3264 (95.6)1012 (99.8)6272 (45.9)
 Missing/NA1847 (100)2110 (100)0 (0)0 (0)0 (0)3201 (100)7158 (52.3)
  • Values presented are number (%). Percentages may not sum to 100% due to rounding.

  • COPD, chronic obstructive pulmonary disease; ICCC, International Community-Acquired Pneumonia (CAP) Collaboration Cohort; NA, not available.