Table 3

Relations of baseline cognitive function variables to mortality after first-ever stroke/TIA

All stroke/TIA (n=155), 84 died during follow-upBrain infarction (n=97), 53 died during follow-up
Adjusted for age at baselineAdjusted for age at baseline, education and social groupMultivariable adjusted modelsAdjusted for age at baselineAdjusted for age at baseline, education and social groupMultivariable adjusted models
Models AModels BModels CModels AModels BModels C
Trail Making Test-A
 As continuous variable1.45 (1.15 to 1.82)1.67 (1.24 to 2.23)1.88 (1.31 to 2.71)1.27 (0.92 to 1.76)1.47 (0.96 to 2.25)1.45 (0.97 to 2.17)
p=0.002p=0.001p=0.001p=0.137p=0.075p=0.068
 Tertile 1111111
 Tertile 21.47 (0.84 to 2.56)1.54 (0.73 to 3.27)2.09 (0.85 to 5.11)1.54 (0.76 to 3.09)1.41 (0.51 to 3.86)1.91 (0.82 to 4.47)
p=0.173p=0.258p=0.107p=0.226p=0.505p=0.133
 Tertile 31.84 (1.07 to 3.17)2.26 (1.13 to 4.53)2.90 (1.24 to 6.77)1.33 (0.65 to 2.73)1.43 (0.54 to 3.75)1.59 (0.64 to 3.92)
p=0.027p=0.021p=0.014p=0.442p=0.468p=0.315
Trail Making Test-B
 As continuous variable1.20 (0.96 to 1.51)1.79 (1.21 to 2.66)2.01 (1.28 to 3.15)1.00 (0.74 to 1.35)1.63 (0.90 to 2.95)1.15 (0.77 to 1.72)
p=0.115p=0.004p=0.002p=0.985p=0.108p=0.488
 Tertile 1111111
 Tertile 21.55 (0.86 to 2.81)1.57 (0.70 to 3.53)2.11 (0.82 to 5.46)0.83 (0.39 to 1.76)0.72 (0.21 to 2.43)0.74 (0.30 to 1.85)
p=0.149p=0.275p=0.124p=0.632p=0.597p=0.521
 Tertile 31.63 (0.91 to 2.92)3.07 (1.22 to 7.73)3.53 (1.21 to 10.34)0.96 (0.47 to 1.96)1.53 (0.42 to 5.49)1.40 (0.58 to 3.35)
p=0.103p=0.017p=0.021p=0.915p=0.516p=0.452
MMSE
 Group 30 points111111
 Group ≤27 points1.22 (0.63 to 2.34)1.35 (0.55 to 3.31)0.81 (0.23 to 2.86)0.52 (0.22 to 1.22)0.71 (0.21 to 2.39)0.54 (0.17 to 1.71)
p=0.558p=0.518p=0.746p=0.132p=0.584p=0.293
 Group 28 points1.56 (0.80 to 3.04)1.92 (0.84 to 4.43)1.80 (0.65 to 4.97)1.17 (0.51 to 2.67)2.08 (0.67 to 6.45)1.09 (0.36 to 3.32)
p=0.197p=0.123p=0.259p=0.715p=0.205p=0.874
 Group 29 points1.03 (0.55 to 1.91)1.35 (0.61 to 2.98)1.27 (0.53 to 3.04)0.63 (0.26 to 1.49)0.85 (0.24 to 2.94)0.42 (0.14 to 1.26)
p=0.928p=0.456p=0.596p=0.294p=0.795p=0.122
  • Data are presented as Cox proportional HRs (95% CIs) for a 1SD increase in the continuous variables or transfer from one level to another of the dichotomous variables.

  • MMSE 30 points and TMT-A and -B tertile 1 were used as references.

  • MMSE, Mini-Mental State Examination; TIA, transient ischaemic attack.