Joint model of SNPs individually associated with log(BMI)
| Gene | SNP | MA | Effect | p Value |
| FTO | rs17817449 | G | 2.2 | 0.007 |
| LEP | rs10954174 | A | −3.2 | 0.005 |
| LEP | rs6966536 | G | 2.7 | 0.020 |
| MC4R | rs17782313 | C | −2.0 | 0.028 |
The model explains 16.4% of the covariation in log(BMI).
p Values are from the joint model, so they are adjusted for age, sex and sex-specific pubertal stage and all other SNPs in the model.
Effect = estimated % change in BMI of each minor allele, independent of other confounding variables (age, sex and sex-specific pubertal stage) and all other SNPs in the model (908 adolescents included in model).
BMI, body mass index; MA, minor allele; SNP, single nucleotide polymorphism.