Table 4

Main regions showing FA, λ1 and λ23 values in patients with COPD compared with healthy controls

MNI (peak)			Voxels (mm³)	White matter tract	Corresponding cortical area	FA value		λ1 (×10³ mm²/s)		λ23 (×10³ mm²/s)
x	y	z	Voxels (mm³)	White matter tract	Corresponding cortical area	COPD	Control	COPD	Control	COPD	Control
1	10	16	240	Fornix	Fornix	0.248 (0.067)	0.289 (0.073)	2.586 (0.314)	2.406 (0.0321)	1.809 (0.295)	1.577 (0.262)*
−26	−69	1	191		Left lingual gyrus	0.259 (0.042)	0.283 (0.046)	1.450 (0.240)	1.370 (0.224)	0.992 (0.185)	0.896 (0.168)*
27	−53	3	147	Lingual gyrus	Right lingual gyrus	0.265 (0.065)	0.290 (0.056)	1.381 (0.239)	1.346 (0.227)	0.955 (0.242)	0.891 (0.215)*
−23	−19	−24	77	Parahippocampus	Left Parahippocampus	0.268 (0.042)	0.319 (0.046)	1.234 (0.057)	1.189 (0.052)	0.869 (0.148)	0.771 (0.125)*
38	−24	−24	77	Fusiform gyrus	Right fusiform gyrus	0.231 (0.037)	0.248 (0.046)	1.053 (0.063)	1.094 (0.073)	0.774 (0.030)	0.723 (0.032)*
−10	−91	17	204	Optic radiation	Left occipital cortex	0.234 (0.043)	0.277 (0.041)	1.037 (0.038)	1.020 (0.031)	0.752 (0.063)	0.693 (0.051)*
25	−86	−5	200	Optic radiation	Right occipital cortex	0.369 (0.099)	0.409 (0.122)	1.171 (0.014)	1.177 (0.171)	0.649 (0.057)	0.601 (0.071)*
−9	−72	45	94	SCR	Left precuneus	0.283 (0.053)	0.317 (0.056)	1.099 (0.032)	1.069 (0.041)	0.726 (0.075)	0.665 (0.065)*
9	−66	37	57	SCR	Right precuneus	0.251 (0.030)	0.280 (0.044)	1.044 (0.032)	1.018 (0.023)	0.868 (0.073)	0.731 (0.084)*
−15	−51	62	57	SCR	Left superior parietal lobule	0.267 (0.043)	0.294 (0.043)	1.130 (0.051)	1.082 (0.025)	0.724 (0.039)	0.671 (0.045)*
16	−45	64	66	SCR	Right superior parietal lobule	0.251 (0.043)	0.294 (0.051)	1.176 (0.117)	1.107 (0.094)	0.805 (0.056)	0.762 (0.056)*
−45	−53	31	44	SLF	Left supramarginal gyrus	0.221 (0.027)	0.239 (0.026)	1.088 (0.020)	1.076 (0.040)	0.935 (0.090)	0.873 (0.071)*
37	−68	21	63	SLF	Right supramarginal gyrus	0.220 (0.025)	0.237 (0.025)	1.116 (0.039)	1.090 (0.052)	0.773 (0.076)	0.715 (0.007)*
−48	0	−16	43	ILF	Left superior temporal gyrus	0.244 (0.013)	0.270 (0.021)	1.060 (0.030)	0.984 (0.015)	0.758 (0.025)	0.714 (0.037)*
53	−46	−6	41	ILF	Right middle temporal gyrus	0.206 (0.016)	0.241 (0.024)	1.025 (0.016)	1.006 (0.021)	1.605 (0.167)	1.340 (0.139)*

Data are presented as means (SD).
*p<0.05.
COPD, chronic obstructive pulmonary disease; FA, fractional anisotropy; ILF, inferior longitudinal fasciculus; SCR, superior corona radiata; SLF, superior longitudinal fasciculus.