Table 3

Model with all universally available baseline variables

	HR	Lower CI	Upper CI	p Value
Sex × digoxin interaction	1.02	0.95	1.09	0.65
Digoxin use	1.00	0.95	1.05	0.89
Female sex	0.86	0.83	0.90	<0.0001
Year of CHF diagnosis	0.99	0.98	0.99	<0.0001
Age 50–64 years	0.42	0.40	0.44	<0.0001
Age 65–74 years	0.58	0.56	0.60	<0.0001
Hypertension	0.91	0.88	0.94	<0.0001
Stroke	1.34	1.29	1.40	<0.0001
MI	1.15	1.11	1.20	<0.0001
COPD	1.36	1.30	1.43	<0.0001
Fracture	1.08	1.03	1.14	0.001
Diabetes	1.34	1.28	1.40	<0.0001
Atrial fibrillation	0.93	0.89	0.97	0.001
Loop diuretic use	1.27	1.23	1.32	<0.0001
Potassium-sparing diuretic use	1.07	1.03	1.11	0.00
Thiazide diuretic	1.03	0.99	1.07	0.16
Oral anticoagulant use	0.92	0.87	0.98	0.001
β Blocker use	0.83	0.79	0.86	<0.0001
ACE use	0.97	0.93	1.00	0.07
ARB use	0.90	0.82	0.98	0.01
CCB use	0.93	0.90	0.97	0.001

ARB, angiotensin receptor blocker; CCB, calcium channel blocker; COPD, chronic obstructive pulmonary disease; MI, myocardial infarction.