Differences in baseline profiles between the converters to AD and non-converters
| SEAD-J | ADNI | |||
| Conv/non-conv | p Value | Conv/non-conv | p Value | |
| 1-year conversion | ||||
| MMSE | 25.3±1.3/26.6±1.9 | 0.002 | 26.8±1.8/27.2/1.7 | NS |
| Modified MMSE | 21.6±1.3/22.6±1.8 | 0.012 | 21.8±1.7/22.5±1.5 | NS |
| WMS-R LM | 0.7±1.3/1.9±1.8 | 0.003 | 2.5±2.3/4.2±2.7 | 0.004 |
| GDS | 4.3±2.0/4.2±2.4 | 0.003 | 1.3±1.4/1.7±1.4 | NS |
| Age (yrs) | 70.6±6.9/71.6±6.7 | NS | 75.5±6.1/75.7±7.3 | NS |
| Education (yrs) | 12.1±3.1/11.5±3.0 | NS | 15.8±2.8/15.9±2.9 | NS |
| 1–2-year conversion | ||||
| MMSE | 25.9±1.8/26.4±1.9 | 0.001 | 27.1±1.6/27.3±1.6 | NS |
| Modified MMSE | 22.1±1.5/22.5±2.0 | NS | 22.5±1.5/22.5±1.4 | NS |
| WMS-R LM | 1.6±1.9/1.9±1.9 | NS | 3.8±2.7/4.3±2.7 | NS |
| GDS | 4.9±2.6/3.9±2.1 | NS | 1.6±1.2/1.5±1.4 | NS |
| AGE (yrs) | 70.9±6.4/71.5±6.5 | NS | 73.7±7.6/75.9±6.8 | NS |
| Education (yrs) | 12.4±3.4/11.7±3.1 | NS | 16.6±2.5/15.8±2.9 | NS |
Values are mean±SD. 1-year conversion, AD conversion within 1 year after inclusion; 1–2-year conversion, AD conversion from 1 year to 2 years after inclusion.
AD, Alzheimer's disease; ADNI, Alzheimer's Disease Neuroimaging Initiative; Conv, AD converters; GDS, Geriatric Depression Scale; MMSE, Mini-Mental Status Examination; non-conv, AD non-converters; NS, no significance; SEAD-J, Studies on Diagnosis of Early Alzheimer's Disease—Japan; WMS-R LM, Logical Memory subset of the Wechsler Memory Scale Revised.