Table 1

Baseline characteristics of patients with vEDS and age- and sex-matched healthy controls

VariablevEDS patients, n (%) or median (Q1; Q3)Controls, n (%) or median (Q1; Q3)Univariate p value
N1746
Age33 (24; 44)36 (25; 45)NS
Male5 (29)13 (28)NS
Periodontal features
 Plaque index30 (20; 54)20 (13; 60)NS
 Gingival index1 (0; 1)1 (0; 1)NS
 Probing bleeding index2 (1; 3)1 (0; 1)0.0003
 Thinness16 (94)20 (43)0.0003
Temporomandibular features
 TMJ group 12 (12)2 (4)NS
 TMJ group 212 (71)8 (17)<0.0001
 TMJ group 310 (59)3 (7)3.10−5
 Total TMJ14 (82)11 (24)<0.0001
 Pain7 (41)3 (100)NS
Dental features15 (94)23 (50)0.0020
 Pulp shape modification12 (75)14 (30)0.0019
 Root fusion8 (50)9 (20)0.0262
 Exceeding root length11 (69)1 (2)10−7
 DFMT4 (2; 11)7 (2; 9)NS
  • Plaque index is defined by (number of tooth with plaque/total number of tooth) ×100. Gingival index is defined by extent of gingival inflammation and staged from 0 to 3. DMF-T index9 is defined by decayed, missing and filled teeth, and ranges from 0 to 28 according to number of diseased teeth.

  • DMF-T, ‘decayed/missing/filled teeth index’; TMJ, temporomandibular joint; vEDS, vascular Ehlers–Danlos syndrome.