Costs
| Parameter | Base case values | Range tested |
| 1. Cost of interventions | NICE21 | |
| TST | £16 | £16–£64 |
| IGRA | £44.78 | £30–£120 |
| Chest radiograph | £28 | |
| Cambridge TB Service 2010 NHS National Tariff22 | ||
| TB treatment | £1637 | 0.5–2 times |
| Contact tracing | £426 | 0.5–2 times |
| LTBI treatment | £647 | 0.5–2 times |
| Hepatitis treatment | £640 | 0.5–2 times |
| 2. Healthcare worker costs | Cambridge TB Service 2010 NHS Pay 2/201023 | |
| Time to attend for TB treatment | £662 | 0.5–2 times |
| Time to attend for contact tracing | £95 | 0.5–2 times |
| Time to attend for LTBI treatment | £172 | 0.5–2 times |
| Time for hepatitis treatment | £114 | 0.5–2 times |
| 3. Discount rate | 0.05 |
TB treatment costs are derived from the NHS National Tariff 2010–201122 applied to the Cambridge TB service. Healthcare worker costs are derived from the NHS Pay Circular (AforC) 2/2010,23 point 26 £30 460, plus 22% overheads £37 161 per annum, applied to the Cambridge TB service. Total model costs for TB treatment are TB treatment, plus contact tracing ×5 contacts per case,19 plus healthcare worker time costs, £4908; for LTBI, LTBI treatment plus healthcare worker time costs, £819 and for hepatitis, hepatitis treatment plus healthcare worker time costs, £755 (supplementary table 1).
IGRA, interferon-gamma release assay; LTBI, latent tuberculosis infection; TB, tuberculosis; TST, tuberculin skin test.