Table 3

HRs of study end points

EventsUnivariateMultivariate*Multivariate
HR (95% CI)p ValueHR (95% CI)p ValueHR (95% CI)p Value
All-cause mortality
 Overweight456 (15%)0.72 (0.63 to 0.82)<0.0010.75 (0.66 to 0.86)<0.0010.90 (0.72 to 1.12)0.335
 Obese159 (13%)0.61 (0.51 to 0.74)<0.0010.72 (0.60 to 0.87)0.0011.07 (0.80 to 1.43)0.663
Cardiac death
 Overweight198 (7%)0.77 (0.63 to 0.94)0.0110.81 (0.66 to 0.99)0.0441.05 (0.71 to 1.57)0.800
 Obese77 (6%)0.73 (0.56 to 0.95)0.0190.82 (0.62 to 1.08)0.1521.02 (0.60 to 1.75)0.939
Non-fatal MI
 Overweight138 (5%)0.81 (0.63 to 1.04)0.0950.79 (0.61 to 1.01)0.0560.75 (0.57 to 0.98)0.036
 Obese79 (6%)1.12 (0.84 to 1.49)0.4341.03 (0.77 to 1.38)0.8440.88 (0.63 to 1.24)0.472
Cardiac death or non-fatal MI
 Overweight336 (13%)0.84 (0.71 to 0.99)0.0380.83 (0.70 to 0.99)0.0330.95 (0.74 to 1.21)0.658
 Obese156 (15%)0.87 (0.70 to 1.07)0.1860.87 (0.69 to 1.08)0.2020.94 (0.68 to 1.30)0.722
  • * Adjusted for all baseline characteristics.

  • Adjusted for all baseline characteristics and optimal medication.

  • MI, myocardial infarction.