Table 5

Effect of weekly vitamin A supplementation on postneonatal deaths by cause of death; intention-to-treat analyses, all live births from 1 June 2003 to 30 September 2008

PlaceboVitamin A
Infant-years of follow-up23 80024 097
Total postneonatal deaths662681
 Infection-specific deaths (n)479503
 Infection-specific deaths/1000 child-years20.1320.87
 Adjusted HR* (95% CI)1.001.04 (0.90 to 1.19)
 p Value0.61
   Pneumonia-specific deaths (n)152146
   Pneumonia-specific deaths/1000 child-years6.396.06
   Adjusted HR* (95% CI)1.000.95 (0.75 to 1.21)
   p Value0.67
   Malaria-specific deaths (n)115113
   Malaria-specific deaths/1000 child-years4.834.69
   Adjusted HR* (95% CI)1.000.97 (0.74 to 1.27)
   p Value0.83
   Diarrhoea-specific deaths (n)6070
   Diarrhoea-specific deaths/1000 child-years2.522.90
   Adjusted HR* (95% CI)1.001.15 (0.82 to 1.62)
   p Value0.42
   Measles-specific deaths (n)42
   Measles-specific deaths/1000 child-years0.170.08
   Adjusted HR* (95% CI)1.000.49 (0.09 to 2.69)
   p Value0.41
  Other infection
   Other infection deaths (n)148172
   Other infection-specific deaths/1000 child-years6.227.14
   Adjusted HR* (95% CI)1.001.15 (0.91 to 1.45)
   p Value0.24
Other deaths
 Other deaths (n)4229
 Other deaths/1000 child-years1.761.20
 Adjusted HR* (95% CI)1.000.68 (0.42 to 1.10)
 p Value0.12
 Unexplained deaths (n)106103
 Unexplained deaths/1000 child years4.454.27
 Adjusted HR* (95% CI)1.000.96 (0.72 to 1.27)
 p Value0.78
Cause of death not ascertained
 Unascertained deaths (n)3546
 Unascertained deaths/1000 child years1.471.91
 Adjusted HR* (95% CI)1.001.30 (0.84 to 2.00)
 p Value0.24
  • * Adjusted for clustering by ObaapaVitA cluster of residence.

  • Includes meningitis, tetanus, HIV/AIDS or infection with an unknown cause.

  • Includes congenital abnormality, accident or injury and malignant tumours.