Table 4

Multivariate-adjusted associations between night shift work (continuous years; <20 vs 20+ years) and sex hormones (log-transformed)

Sex hormoneContinuous shift work (years)Dichotomous shift work (<20 vs 20+ years), geometric means (95% CI)
Parameter estimate (p value)<20 years (n=67)20+ years (n=15)p for Diff
Oestradiol (pmol/l)−0.002 (0.87)259.4 (198.4–338.9)269.5 (182.6–397.7)0.84
Oestrone (pmol/l)0.005 (0.48)209.1 (174.3–250.8)258.6 (197.9–337.9)0.11
Progesterone (nmol/l)−0.002 (0.86)7.0 (4.60–10.8)7.5 (4.28–13.2)0.79
Prolactin (μg/l)0.002 (0.79)16.5 (13.4–20.2)15.7 (11.8–20.8)0.71
  • Adjusted for age (years), body mass index (kg/m2), menstrual cycle stage (follicular, mid-cycle, luteal) and OC use (yes/no), recent alcohol consumption (drinks per day), recent caffeine consumption (drinks per day), smoking status (current/never/former) and total and moderate-to-heavy recent physical activity levels (hours per week), as appropriate.